Intramolecular Michael Reaction oftert-Butylsulfinyl Ketimines: Asymmetric Synthesis of 3-Substituted Indanones

2011 ◽  
Vol 13 (24) ◽  
pp. 6564-6567 ◽  
Author(s):  
Santos Fustero ◽  
Elsa Rodríguez ◽  
Lidia Herrera ◽  
Amparo Asensio ◽  
Miguel A. Maestro ◽  
...  
ChemInform ◽  
2014 ◽  
Vol 45 (3) ◽  
pp. no-no
Author(s):  
Santos Fustero ◽  
Lidia Herrera ◽  
Ruben Lazaro ◽  
Elsa Rodriguez ◽  
Miguel A. Maestro ◽  
...  

2015 ◽  
Vol 11 ◽  
pp. 2654-2660 ◽  
Author(s):  
Yusuke Kobayashi ◽  
Ryuta Kuramoto ◽  
Yoshiji Takemoto

The first catalytic asymmetric synthesis of the key intermediate for beraprost has been achieved through an enantioselective intramolecular oxa-Michael reaction of an α,β-unsaturated amide mediated by a newly developed benzothiadiazine catalyst. The Weinreb amide moiety and bromo substituent of the Michael adduct were utilized for the C–C bond formations to construct the scaffold. All four contiguous stereocenters of the tricyclic core were controlled via Rh-catalyzed stereoselective C–H insertion and the subsequent reduction from the convex face.


ChemCatChem ◽  
2019 ◽  
Vol 11 (16) ◽  
pp. 3760-3762 ◽  
Author(s):  
Harry Eastman ◽  
James Ryan ◽  
Beatriz Maciá ◽  
Vittorio Caprio ◽  
Elaine O'Reilly

2013 ◽  
Vol 24 (7) ◽  
pp. 402-408 ◽  
Author(s):  
Nian-hua Luo ◽  
Xiang Sun ◽  
Wen-tao Wei ◽  
Xue-jing Zhang ◽  
Ming Yan

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