Intramolecular Michael Reaction oftert-Butylsulfinyl Ketimines: Asymmetric Synthesis of 3-Substituted Indanones

2011 ◽  
Vol 13 (24) ◽  
pp. 6564-6567 ◽  
Author(s):  
Santos Fustero ◽  
Elsa Rodríguez ◽  
Lidia Herrera ◽  
Amparo Asensio ◽  
Miguel A. Maestro ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Reaction

ChemInform Abstract: Base-Dependent Stereodivergent Intramolecular Aza-Michael Reaction: Asymmetric Synthesis of 1,3-Disubstituted Isoindolines.

ChemInform ◽  
2014 ◽  
Vol 45 (3) ◽  
pp. no-no
Author(s):  
Santos Fustero ◽  
Lidia Herrera ◽  
Ruben Lazaro ◽  
Elsa Rodriguez ◽  
Miguel A. Maestro ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Reaction

scholarly journals Catalytic asymmetric formal synthesis of beraprost

2015 ◽  
Vol 11 ◽  
pp. 2654-2660 ◽  
Author(s):  
Yusuke Kobayashi ◽  
Ryuta Kuramoto ◽  
Yoshiji Takemoto
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Reaction ◽  
Subsequent Reduction ◽  
Formal Synthesis ◽  
Michael Adduct ◽  
Catalytic Asymmetric Synthesis ◽  
Weinreb Amide ◽  
Tricyclic Core ◽  
Catalytic Asymmetric

The first catalytic asymmetric synthesis of the key intermediate for beraprost has been achieved through an enantioselective intramolecular oxa-Michael reaction of an α,β-unsaturated amide mediated by a newly developed benzothiadiazine catalyst. The Weinreb amide moiety and bromo substituent of the Michael adduct were utilized for the C–C bond formations to construct the scaffold. All four contiguous stereocenters of the tricyclic core were controlled via Rh-catalyzed stereoselective C–H insertion and the subsequent reduction from the convex face.

scholarly journals Alcohol Dehydrogenase‐Triggered Oxa‐Michael Reaction for the Asymmetric Synthesis of Disubstituted Tetrahydropyrans and Tetrahydrofurans

ChemCatChem ◽  
2019 ◽  
Vol 11 (16) ◽  
pp. 3760-3762 ◽  
Author(s):  
Harry Eastman ◽  
James Ryan ◽  
Beatriz Maciá ◽  
Vittorio Caprio ◽  
Elaine O'Reilly
Keyword(s):  
Alcohol Dehydrogenase ◽  
Asymmetric Synthesis ◽  
Michael Reaction

Asymmetric synthesis of multicyclic spiro-1,3-indandiones via a cascade Michael/Michael reaction of curcumins and 2-arylidene-1,3-indandiones

2013 ◽  
Vol 24 (7) ◽  
pp. 402-408 ◽  
Author(s):  
Nian-hua Luo ◽  
Xiang Sun ◽  
Wen-tao Wei ◽  
Xue-jing Zhang ◽  
Ming Yan
Keyword(s):  
Asymmetric Synthesis ◽  
Michael Reaction
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