A comparison between flow cytometric assessment of S-phase fraction and Nottingham histologic grade as prognostic instruments in breast cancer

2000 ◽  
Vol 63 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Marie Sundquist ◽  
Sten Thorstenson ◽  
Lars Brudin ◽  
Olle Stål ◽  
Bo Nordenskjöld
Keyword(s):  
Breast Cancer ◽  
S Phase ◽  
Histologic Grade ◽  
Phase Fraction ◽  
Flow Cytometric

scholarly journals DNA flow cytometric analysis of primary operable breast cancer. Relation of ploidy and S-Phase fraction to outcome of patients in NSABP B-04

Cancer ◽  
1991 ◽  
Vol 68 (7) ◽  
pp. 1465-1475 ◽  
Author(s):  
Bernard Fisher ◽  
Nurten Gunduz ◽  
Joseph Costantino ◽  
Edwin R. Fisher ◽  
Carol Redmond ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Flow Cytometric Analysis ◽  
Operable Breast Cancer ◽  
S Phase ◽  
Phase Fraction ◽  
Flow Cytometric ◽  
Primary Operable Breast Cancer

Flow cytometric (DNA content and S-phase fraction) analysis of breast cancer

Cancer ◽  
1993 ◽  
Vol 71 (S6) ◽  
pp. 2151-2153 ◽  
Author(s):  
John G. Batsakis ◽  
Nour Sneige ◽  
Adel K. El-Naggar
Keyword(s):  
Breast Cancer ◽  
Dna Content ◽  
S Phase ◽  
Phase Fraction ◽  
Flow Cytometric

The Flow-Cytometric Analysis of DNA Content and S-Phase Fraction (SPF) of Human Breast Cancer

1989 ◽  
Vol 185 (5) ◽  
pp. 694-697 ◽  
Author(s):  
M. Eskelinen ◽  
S. Nordling ◽  
J. Puittinen ◽  
E. Pesonen ◽  
Y. Collan
Keyword(s):  
Breast Cancer ◽  
Dna Content ◽  
Human Breast Cancer ◽  
Flow Cytometric Analysis ◽  
S Phase ◽  
Phase Fraction ◽  
Human Breast ◽  
Flow Cytometric

Comparison of PCNA/cyclin immunohistochemistry with flow cytometric S-phase fraction in breast cancer

1992 ◽  
Vol 22 (2) ◽  
pp. 111-118 ◽  
Author(s):  
D. W. Visscher ◽  
S. Wykes ◽  
J. Kubus ◽  
J. D. Crissman
Keyword(s):  
Breast Cancer ◽  
S Phase ◽  
Phase Fraction ◽  
Flow Cytometric

scholarly journals Association between flow cytometric S-phase fraction and apoptotic rate in breast cancer

Cytometry ◽  
1996 ◽  
Vol 26 (4) ◽  
pp. 281-285 ◽  
Author(s):  
Michael K. Samoszuk ◽  
Gretchen Sallash ◽  
Kevin Chen ◽  
Esther Carlton ◽  
Teri Oldaker
Keyword(s):  
Breast Cancer ◽  
S Phase ◽  
Phase Fraction ◽  
Flow Cytometric

scholarly journals Flow Cytometric DNA Index and S-Phase Fraction in Breast Cancer in Relation to Other Prognostic Variables and to Clinical Outcome

1992 ◽  
Vol 31 (2) ◽  
pp. 157-165 ◽  
Author(s):  
MÅRten Fernö ◽  
Bo Baldetorp ◽  
ÅKe Borg ◽  
HÅKan Olsson ◽  
Helgi Sigurdsson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Outcome ◽  
S Phase ◽  
Phase Fraction ◽  
Prognostic Variables ◽  
Dna Index ◽  
Flow Cytometric

scholarly journals Different calculation methods for flow cytometric S-phase fraction: Prognostic implications in breast cancer?

Cytometry ◽  
1998 ◽  
Vol 33 (4) ◽  
pp. 385-393 ◽  
Author(s):  
Bo Baldetorp ◽  
Olle St�l ◽  
Olaf Ahrens ◽  
Cees Cornelisse ◽  
Willem Corver ◽  
...  
Keyword(s):  
Breast Cancer ◽  
S Phase ◽  
Phase Fraction ◽  
Calculation Methods ◽  
Flow Cytometric ◽  
Prognostic Implications

scholarly journals Optimizing flow cytometric DNA ploidy and S-phase fraction as independent prognostic markers for node-negative breast cancer specimens

Cytometry ◽  
2001 ◽  
Vol 46 (3) ◽  
pp. 121-135 ◽  
Author(s):  
C.B. Bagwell ◽  
G.M. Clark ◽  
F. Spyratos ◽  
A. Chassevent ◽  
P.-O. Bendahl ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Markers ◽  
Dna Ploidy ◽  
S Phase ◽  
Phase Fraction ◽  
Node Negative ◽  
Flow Cytometric ◽  
Node Negative Breast Cancer

scholarly journals Evaluation of Prognostic Factors Following Flow-Cytometric DNA Analysis after Cytokeratin Labelling: I. Breast Cancer

2002 ◽  
Vol 24 (4-5) ◽  
pp. 135-145 ◽  
Author(s):  
Pauline Wimberger ◽  
Peter Hillemanns ◽  
Thomas Kapsner ◽  
Hermann Hepp ◽  
Rainer Kimmig
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Tumor Cells ◽  
Dna Ploidy ◽  
Gynecologic Oncology ◽  
Univariate Analysis ◽  
Prognostic Significance ◽  
S Phase ◽  
Phase Fraction ◽  
Flow Cytometric

In gynecologic oncology valid prognostic factors are necessary to estimate the course of disease and to define biologically similar subgroups for analysis of therapeutic efficacy. The presented study is a prospective study concerning prognostic significance of DNA ploidy and S‐phase fraction in breast cancer following enrichment of tumor cells by cytokeratin labelling. Epithelial cells were labeled by FITC‐conjugated cytokeratin antibody (CK 5, 6, 8, and CK 17) prior to flow cytometric cell cycle analysis in 327 fresh specimens of primary breast cancer. Univariate analysis in breast cancer detected the prognostic significance of DNA‐ploidy, S‐phase fraction and CV (coefficient of variation) of G0G1‐peak of tumor cells for clinical outcome, especially for nodal‐negative patients. Multivariate analysis could not confirm prognostic evidence of DNA‐ploidy and S‐phase fraction. In conclusion, in breast cancer no clinical significance for determination of DNA‐parameters was found.

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