scholarly journals High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer

1999 ◽  
Vol 10 (10) ◽  
pp. 1233-1240 ◽  
Author(s):  
H.R. Hendriks ◽  
H.H. Fiebig ◽  
R. Giavazzi ◽  
S.P. Langdon ◽  
J.M. Jimeno ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Antitumour Activity ◽  
Small Cell ◽  
Small Cell Lung ◽  
Human Tumour ◽  
Human Tumour Xenografts ◽  
Tumour Xenografts

Antitumour activity and schedule dependency of 8-chloroadenosine-3′,5′-monophosphate (8-ClcAMP) against human tumour xenografts

1998 ◽  
Vol 34 (3) ◽  
pp. 384-388 ◽  
Author(s):  
S.P. Langdon ◽  
A.A. Ritchie ◽  
M. Muir ◽  
M. Dodds ◽  
A.F. Howie ◽  
...  
Keyword(s):  
Antitumour Activity ◽  
Human Tumour ◽  
Human Tumour Xenografts ◽  
Tumour Xenografts

Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts

1999 ◽  
Vol 35 (3) ◽  
pp. 512-520 ◽  
Author(s):  
B.T Hill ◽  
H.-H Fiebig ◽  
W.R Waud ◽  
M.-F Poupon ◽  
F Colpaert ◽  
...  
Keyword(s):  
Antitumour Activity ◽  
Human Tumour ◽  
Human Tumour Xenografts ◽  
Tumour Xenografts

scholarly journals Synthesis, Characterization and In Vitro Antitumour Activity of Di-n-Butyl, Tri-n-Butyl and Triphenyltin 3,6-Dioxaheptanoates and 3,6,9-Trioxadecanoates

1998 ◽  
Vol 5 (4) ◽  
pp. 189-196 ◽  
Author(s):  
Martine Kemmer ◽  
Marcel Gielen ◽  
Monique Biesemans ◽  
Dick de Vos ◽  
Rudolph Willem
Keyword(s):  
Lung Cancer ◽  
Ovarian Cancer ◽  
Antitumour Activity ◽  
Small Cell ◽  
Breast Cancers ◽  
Human Origin ◽  
Small Cell Lung ◽  
Derivatives Of ◽  
Mcf 7

A series of di- and triorganotin 3,6-dioxaheptanoates and 3,6,9-trioxadecanoates were synthesized and characterized by H1, C13 and S117n NMR, electrospray mass and S119mn Mössbauer spectroscopy, as well as elemental analysis. Their in vitro antitumour activity against seven tumoural cell lines of human origin, two breast cancers (MCF-7, EVSA-T), a colon carcinoma (WiDr), an ovarian cancer (IGROV), a melanoma (M 19 MEL), a renal cancer (A 498) and a non small cell lung cancer (H 226), is reported. They are characterized by similar inhibition doses ID50 as the analogous di- and triorganotin derivatives of 4-carboxybenzo-15-crown-5 and -18-crown-6 and in some cases by much lower ID50 values than clinically used reference compounds such as doxorubicine and methotrexate.

Comparative antitumour activity of vinblastine-isoleucinate and related vinca alkaloids in human tumour xenografts

1992 ◽  
Vol 28 (4-5) ◽  
pp. 767-773 ◽  
Author(s):  
Hans R. Hendriks ◽  
Simon Langdon ◽  
Dietmar P. Berger ◽  
Knut Breistøl ◽  
Heinz H. Fiebig ◽  
...  
Keyword(s):  
Antitumour Activity ◽  
Vinca Alkaloids ◽  
Human Tumour ◽  
Human Tumour Xenografts ◽  
Tumour Xenografts

The antitumour activity of the prodrug N-l-leucyl-doxorubicin and its parent compound doxorubicin in human tumour xenografts

1998 ◽  
Vol 34 (10) ◽  
pp. 1602-1606 ◽  
Author(s):  
K. Breistøl ◽  
H.R. Hendriks ◽  
D.P. Berger ◽  
S.P. Langdon ◽  
H.H. Fiebig ◽  
...  
Keyword(s):  
Antitumour Activity ◽  
Parent Compound ◽  
Human Tumour ◽  
Human Tumour Xenografts ◽  
Tumour Xenografts

BNP7787, a novel protector against platinum-related toxicities, does not affect the efficacy of cisplatin or carboplatin in human tumour xenografts

2002 ◽  
Vol 38 (8) ◽  
pp. 1148-1156 ◽  
Author(s):  
E Boven ◽  
M Verschraagen ◽  
T.M Hulscher ◽  
C.A.M Erkelens ◽  
F.H Hausheer ◽  
...  
Keyword(s):  
Human Tumour ◽  
Human Tumour Xenografts ◽  
Tumour Xenografts
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