Reciprocal Effects of Personality and Alcohol Use Trajectories from Early-Adolescence to Young Adulthood

2013 ◽  
Author(s):  
Daniel M. Blonigen
2018 ◽  
Vol 31 (02) ◽  
pp. 457-469 ◽  
Author(s):  
Jinni Su ◽  
Andrew J. Supple ◽  
Esther M. Leerkes ◽  
Sally I-Chun Kuo

AbstractUsing a large and nationally representative sample, we examined how adolescents’ 5-HTTLPR genotype and perceived parenting quality independently and interactively associated with trajectories of alcohol use from early adolescence to young adulthood and whether/how gender may moderate these associations. The sample for this study included 13,749 adolescents (53.3% female; 56.3% non-Hispanic White, 21.5% Black, 16.0% Hispanic, and 6.1% Asian) followed prospectively from adolescence to young adulthood. Using growth mixture modeling, we identified four distinct trajectories of alcohol use (i.e., persistent heavy alcohol use, developmentally limited alcohol use, late-onset heavy alcohol use, and non/light alcohol use). Results indicated that the short allele of 5-HTTLPR was associated with higher risk of membership in the persistent and the late-onset heavy alcohol use trajectories. Parenting quality was associated with lower likelihoods of following the persistent heavy and the developmentally limited alcohol use trajectories but was not associated with risk of membership for the late-onset heavy drinking trajectory. 5-HTTLPR interacted with parenting quality to predict membership in the persistent heavy alcohol use trajectory for males but not for females. Findings highlighted the importance of considering the heterogeneity in trajectories of alcohol use across development and gender in the study of Gene Environment interactions in alcohol use.


2012 ◽  
Vol 53 (7) ◽  
pp. 798-805 ◽  
Author(s):  
Suzanne H.W. Mares ◽  
Anna Lichtwarck-Aschoff ◽  
William J. Burk ◽  
Haske van der Vorst ◽  
Rutger C.M.E. Engels

2015 ◽  
Vol 39 (2) ◽  
pp. 94-106 ◽  
Author(s):  
D. M. Prince ◽  
M. C. Adrian ◽  
H. L. Storer ◽  
N. Namkung ◽  
K. Thompson ◽  
...  

2015 ◽  
Vol 39 (11) ◽  
pp. 2163-2170 ◽  
Author(s):  
Daniel M. Blonigen ◽  
C. Emily Durbin ◽  
Brian M. Hicks ◽  
Wendy Johnson ◽  
Matt McGue ◽  
...  

2016 ◽  
Vol 4 ◽  
pp. 13-17 ◽  
Author(s):  
Christopher P. Salas-Wright ◽  
Jennifer M. Reingle Gonzalez ◽  
Michael G. Vaughn ◽  
Seth J. Schwartz ◽  
Katelyn K. Jetelina

2020 ◽  
Author(s):  
Joseph D. Deak ◽  
D. Angus Clark ◽  
Mengzhen Liu ◽  
C. Emily Durbin ◽  
William G. Iacono ◽  
...  

Objective: Molecular genetic studies of alcohol and nicotine have identified many genome-wide loci. We examined the predictive utility of drinking and smoking polygenic scores (PGS) for alcohol and nicotine use from late childhood to early adulthood, substance-specific versus broader-liability PGS effects, and if PGS performance varied between consumption versus pathological use. Methods: Latent growth curve models with structured residuals were used to assess the predictive utility of drinks per week and regular smoking PGS for measures of alcohol and nicotine consumption and problematic use from age 14 to 34. PGSs were generated from the largest discovery sample for alcohol and nicotine use to date (i.e., GSCAN), and examined for associations with alcohol and nicotine use in the Minnesota Twin Family Study (N=3225).Results: The drinking PGS was a significant predictor of age 14 problematic alcohol use and increases in problematic use during young adulthood. The smoking PGS was a significant predictor for all nicotine use outcomes. After adjusting for the effects of both PGSs, the smoking PGS demonstrated incremental predictive utility for most alcohol use outcomes and remained a significant predictor of nicotine use trajectories. Conclusions: Higher PGS for drinking and smoking were associated with more problematic levels of substance use longitudinally. The smoking PGS seems to capture both nicotine-specific and non-specific genetic liability for substance use, and may index genetic risk for broader externalizing behavior. Validation of PGS within longitudinal designs may have important clinical implications should future studies support the clinical utility of PGS for substance use disorders.


2021 ◽  
pp. 088626052198973
Author(s):  
Hailee K. Dunn ◽  
Deborah N. Pearlman ◽  
Madeline C. Montgomery ◽  
Lindsay M. Orchowski

Research demonstrates that both peer socialization and underage drinking play a significant role in teen dating violence. However, less is known about the lasting effects of these risk factors on boys’ ability to form healthy romantic relationships as they get older. The present study examined whether boys who perceived their peers would respect them more for having sex and those who engaged in past year heavy alcohol use would be more likely to perpetrate sexual intimate partner violence (IPV) in young adulthood compared to boys who did not endorse perceived peer approval for sex or report past year heavy drinking. Analyses were conducted using a sample of boys ( n = 1,189) from Waves I and III of the National Longitudinal Study of Adolescent to Adult Health (Add Health). A logistic regression was conducted to assess the relationship between perceived peer approval to have sex and heavy alcohol use at Wave I and sexual IPV at Wave III, after adjusting for demographic factors and other correlates of sexual IPV at Wave I, including age, race/ethnicity, sexual initiation in adolescence, parental attachment, annual family income, and neighborhood poverty. Boys who believed they would gain peer respect by having sex and boys who reported getting drunk in the last 12 months, regardless of how often, were significantly more likely to report sexual IPV in young adulthood compared to boys who did not endorse either of these factors. Targeting boys’ perceived peer norms regarding sexual activity and heavy alcohol use may therefore be especially important for preventing sexual IPV later in life.


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