scholarly journals Sodium-chloride-induced protection in nephrotoxic acute renal failure: Independence from renin

1979 ◽  
Vol 16 (4) ◽  
pp. 481-490 ◽  
Author(s):  
Anil Bidani ◽  
Paul Churchill ◽  
Larry Fleischmann
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Sodium Chloride

The Effect of Indomethacin and Prostaglandin (PGE2) on Renal Failure Due to Glycerol in Saline-Loaded Rats

1975 ◽  
Vol 49 (5) ◽  
pp. 507-510 ◽  
Author(s):  
N. Papanicolaou ◽  
P. Callard ◽  
J. Bariety ◽  
P. Milliez
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Sodium Chloride ◽  
Protective Effect ◽  
Extracellular Space ◽  
Subcutaneous Injection ◽  
Saline Infusion ◽  
Conscious Rats

1. Acute renal failure was induced in conscious rats by subcutaneous injection of glycerol. 2. Expansion of the extracellular space by infusion of 150 mmol/l sodium chloride (saline) partly protected the animals against acute renal failure. 3. This protective effect of saline infusion disappeared when the animals were treated with indomethacin. This effect could be reversed by the addition of prostaglandin (PGE2) to the saline infusion. 4. We suggest that prostaglandins may be involved in mediating the protection afforded by saline infusion against acute renal failure due to glycerol.

Pathophysiology of acute renal failure

1973 ◽  
Vol 131 (6) ◽  
pp. 911-928 ◽  
Author(s):  
W. Flamenbaum
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure
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