Caspase-2: an orphan enzyme out of the shadows

Oncogene ◽

10.1038/onc.2017.169 ◽

2017 ◽

Vol 36 (39) ◽

pp. 5441-5444 ◽

Author(s):

J Forsberg ◽

B Zhivotovsky ◽

M Olsson

Keyword(s):

Caspase 2 ◽

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Faculty Opinions recommendation of Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1019545.221456 ◽

2004 ◽

Author(s):

Sharad Kumar

Keyword(s):

Apoptosis Pathway ◽

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Faculty Opinions recommendation of The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1018436.209500 ◽

2004 ◽

Author(s):

Eui-Ju Choi

Keyword(s):

Protein Complex ◽

Genotoxic Stress ◽

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Faculty Opinions recommendation of Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1109010.568116 ◽

2008 ◽

Author(s):

Sharad Kumar

Keyword(s):

Caspase 3 ◽

Apoptotic Response ◽

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Faculty Opinions recommendation of c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108252.564273 ◽

2008 ◽

Author(s):

David Andrews

Keyword(s):

Cytotoxic Drug ◽

Drug Induced ◽

Caspase 2 ◽

Induced Apoptosis

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Faculty Opinions recommendation of Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717952410.793457864 ◽

2012 ◽

Author(s):

Christoph Borner

Keyword(s):

Cleavage Specificity ◽

Effector Caspases ◽

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Faculty Opinions recommendation of IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717959717.793477084 ◽

2013 ◽

Author(s):

Miles Wilkinson

Keyword(s):

Er Stress ◽

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Faculty Opinions recommendation of IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717959717.793462943 ◽

2012 ◽

Author(s):

Karin Romisch

Keyword(s):

Er Stress ◽

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Metabolic Regulation of Caspase 2 in Breast Cancer

10.21236/ada504651 ◽

2009 ◽

Author(s):

Marisa Buchakjian

Keyword(s):

Breast Cancer ◽

Metabolic Regulation ◽

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Modulation of Amyloid-β Peptide-Induced Toxicity through Inhibition of JNK Nuclear Localization and Caspase-2 Activation

Journal of Alzheimer s Disease ◽

10.3233/jad-2010-100909 ◽

2010 ◽

Vol 22 (2) ◽

pp. 557-568 ◽

Author(s):

Ricardo J.S. Viana ◽

Rita M. Ramalho ◽

Ana F. Nunes ◽

Clifford J. Steer ◽

Cecília M.P. Rodrigues

Keyword(s):

Nuclear Localization ◽

Amyloid Β Peptide ◽

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A novel proteolytic cleavage of ROCK 1 in cell death: Not only by caspases 3 and 7 but also by caspase 2

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2021.02.024 ◽

2021 ◽

Vol 547 ◽

pp. 118-124

Author(s):

Aysun Özdemir ◽

Burçin İbişoğlu ◽

Yaprak Dilber Şimay Demir ◽

Elifnur Benhür ◽

Farzaneh Valipour ◽

...

Keyword(s):

Proteolytic Cleavage ◽

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