scholarly journals Halting 'research waste'

BDJ ◽  
2021 ◽  
Vol 231 (6) ◽  
pp. 317-318
Author(s):  
E. Shamsoddin ◽  
A. Sofi-Mahmudi ◽  
V. Natoli ◽  
T. Franchi ◽  
M. R. Tovani-Palone
Keyword(s):  
Trials ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Katie Gillies ◽  
Iain Chalmers ◽  
Paul Glasziou ◽  
Diana Elbourne ◽  
Jim Elliott ◽  
...  

Abstract Poor recruitment to, and retention in, clinical trials is a source of research waste that could be reduced by more informed choices about participation. Barriers to effective recruitment and retention can be wide-ranging but relevance of the questions being addressed by trials and the outcomes that they are assessing are key for potential participants. Decisions about trial participation should be informed by general and trial-specific information and by considering broader assessments of ‘informedness’ and how they impact on both recruitment and retention. We suggest that more informed decisions about trial participation should encourage personally appropriate decisions, increase recruitment and retention, and reduce research waste and increase its value.


physioscience ◽  
2021 ◽  
Vol 17 (03) ◽  
pp. 97-98
Author(s):  
Roger Hilfiker
Keyword(s):  

BMJ ◽  
2018 ◽  
pp. k4645 ◽  
Author(s):  
Paul Glasziou ◽  
Iain Chalmers
Keyword(s):  

2018 ◽  
Vol 34 (S1) ◽  
pp. 47-47
Author(s):  
Wendy Reijmerink

Introduction:National health research funders are accountable to the public with regard to the societal impact of the research, including health technology assessment (HTA), that they fund. Failing to do so can not only negatively affect public trust in the allocation of resources to funding agencies, but can also lead to public mistrust in science.Methods:We present the results of reducing research waste to ensure societal responsible research, both at an international and national level. In the Netherlands, the National Organization for Health Research and Development (ZonMw) developed an analytical framework to assess its research programs, including the national HTA program.Results:An evaluation of 12 national funding agencies in Australia, Europe and North America demonstrated that certain processes (e.g. how research questions are prioritized or decided) are not transparent. At the international level, health funders believe that they have a joint responsibility not just to seek to advance knowledge, but also to advance the practices of health-related research and research funding. In the Netherlands, ZonMw (HTA) research programs perform well regarding addressing societal relevance (e.g. stakeholder participation) and reasonably well on scientific quality (e.g. international cooperation and knowledge sharing). Efficiency (e.g. encouraging use of existing data and systematic reviews) appears to be less well developed, while integrity (e.g. preventing publication bias) is underexposed.Conclusions:Although ZonMw is doing reasonably well in terms of reducing research waste, it was concluded that more focus on societal impact assessment is needed. To do so funding agencies need to collaborate with all relevant stakeholders. This is especially relevant in the field of HTA where the ambition is to move from evidence to impact.


2016 ◽  
Vol 136 (10) ◽  
pp. 1930-1933 ◽  
Author(s):  
Carsten Flohr ◽  
Stephan Weidinger
Keyword(s):  

Anaesthesia ◽  
2018 ◽  
Vol 73 (6) ◽  
pp. 663-668 ◽  
Author(s):  
J. J. Pandit ◽  
A. F. Merry
Keyword(s):  

2015 ◽  
Vol 25 (suppl_3) ◽  
Author(s):  
J Rathbone ◽  
M Carter ◽  
T Hoffmann ◽  
P Glasziou

Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Shaun Treweek ◽  
Simon Bevan ◽  
Peter Bower ◽  
Matthias Briel ◽  
Marion Campbell ◽  
...  

AbstractThe evidence base available to trialists to support trial process decisions—e.g. how best to recruit and retain participants, how to collect data or how to share the results with participants—is thin. One way to fill gaps in evidence is to run Studies Within A Trial, or SWATs. These are self-contained research studies embedded within a host trial that aim to evaluate or explore alternative ways of delivering or organising a particular trial process.SWATs are increasingly being supported by funders and considered by trialists, especially in the UK and Ireland. At some point, increasing SWAT evidence will lead funders and trialists to ask: given the current body of evidence for a SWAT, do we need a further evaluation in another host trial? A framework for answering such a question is needed to avoid SWATs themselves contributing to research waste.This paper presents criteria on when enough evidence is available for SWATs that use randomised allocation to compare different interventions.


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