Synthesis, X-ray crystal structure, DNA binding, antioxidant and cytotoxicity studies of Ni(ii) and Pd(ii) thiosemicarbazone complexes

A Cu(ii) complex, [Cu(L1Hpy)Cl]2(ClO4)2, of a tridentate pyridoxal Schiff base shows exceptionally high catalytic efficiency (kcat = 3.46 × 105 h−1) for catecholase activity in MeOH solution, the highest value reported in literature so far.

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Synthesis, photophysical properties and DNA binding studies of novel luminescent rhenium(I) complexes. X-Ray crystal structure of [Re(dppn)(CO)3(py)](OTf)

Journal of the Chemical Society Chemical Communications ◽

10.1039/c39950001191 ◽

1995 ◽

pp. 1191 ◽

Cited By ~ 74

Author(s):

Vivian Wing-Wah Yam ◽

Kenneth Kam-Wing Lo ◽

Kung-Kai Cheung ◽

Richard Yuen-Chong Kong

Keyword(s):

Crystal Structure ◽

Dna Binding ◽

Photophysical Properties ◽

Binding Studies ◽

X Ray ◽

Dna Binding Studies

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Synthesis, X-ray crystal structure, DNA/protein binding and cytotoxicity studies of five α-aminophosphonate N-derivatives

Bioorganic Chemistry ◽

10.1016/j.bioorg.2016.10.007 ◽

2016 ◽

Vol 69 ◽

pp. 132-139 ◽

Cited By ~ 11

Author(s):

Qingming Wang ◽

Lei Yang ◽

Hui Ding ◽

Xuanrong Chen ◽

Hua Wang ◽

...

Keyword(s):

Crystal Structure ◽

Protein Binding ◽

X Ray ◽

Cytotoxicity Studies

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Antitumor Activity, X-ray Crystal Structure, and DNA Binding Properties of Thiocoraline A, a Natural Bisintercalating Thiodepsipeptide

Journal of Medicinal Chemistry ◽

10.1021/jm070381s ◽

2007 ◽

Vol 50 (14) ◽

pp. 3322-3333 ◽

Cited By ~ 44

Author(s):

Ana Negri ◽

Esther Marco ◽

Verónica García-Hernández ◽

Alberto Domingo ◽

Antonio L. Llamas-Saiz ◽

...

Keyword(s):

Crystal Structure ◽

Dna Binding ◽

Antitumor Activity ◽

Binding Properties ◽

X Ray ◽

Dna Binding Properties

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Two novel Ag(I) complexes of N-nicotinyl phosphoric triamide derivatives: Synthesis, X-ray crystal structure and in vitro antibacterial and cytotoxicity studies

Inorganica Chimica Acta ◽

10.1016/j.ica.2014.07.029 ◽

2014 ◽

Vol 423 ◽

pp. 107-116 ◽

Cited By ~ 16

Author(s):

Khodayar Gholivand ◽

Foroogh Molaei ◽

Nasrin Oroujzadeh ◽

Rezvan Mobasseri ◽

Hossein Naderi-Manesh

Keyword(s):

Crystal Structure ◽

X Ray ◽

Cytotoxicity Studies ◽

Phosphoric Triamide

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DNA binding studies and antibacterial properties of a new Schiff base ligand containing homopiperazine and products of its reaction with Zn(II), Cu(II) and Co(II) metal ions: X-ray crystal structure of Cu(II) and Zn(II) complexes

Polyhedron ◽

10.1016/j.poly.2019.06.023 ◽

2019 ◽

Vol 170 ◽

pp. 584-592 ◽

Cited By ~ 4

Author(s):

Hassan Keypour ◽

Fatemeh Forouzandeh ◽

Sadegh Salehzadeh ◽

Farshid Hajibabaei ◽

Saeed Feizi ◽

...

Keyword(s):

Crystal Structure ◽

Schiff Base ◽

Dna Binding ◽

Metal Ions ◽

Schiff Base Ligand ◽

Antibacterial Properties ◽

Binding Studies ◽

X Ray ◽

Dna Binding Studies

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Response regulator YycF essential for bacterial growth: X-ray crystal structure of the DNA-binding domain and its PhoB-like DNA recognition motif

FEBS Letters ◽

10.1016/j.febslet.2008.09.007 ◽

2008 ◽

Vol 582 (23-24) ◽

pp. 3434-3438 ◽

Cited By ~ 14

Author(s):

Toshihide Okajima ◽

Akihiro Doi ◽

Ario Okada ◽

Yasuhiro Gotoh ◽

Katsuyuki Tanizawa ◽

...

Keyword(s):

Crystal Structure ◽

Dna Binding ◽

Bacterial Growth ◽

Response Regulator ◽

Dna Recognition ◽

Binding Domain ◽

Dna Binding Domain ◽

X Ray ◽

Recognition Motif

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ChemInform Abstract: The Synthesis and X-Ray Crystal Structure of the Monodentate (S) Thiosemicarbazide and Thiosemicarbazone Complexes (Fe(CO)2L(η5-C5H5))(PF6).

ChemInform ◽

10.1002/chin.199002275 ◽

1990 ◽

Vol 21 (2) ◽

Author(s):

M. J. M. CAMPBELL ◽

E. MORRISON ◽

V. ROGERS ◽

P. K. BAKER ◽

D. C. POVEY ◽

...

Keyword(s):

Crystal Structure ◽

X Ray ◽

Thiosemicarbazone Complexes

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A mononuclear copper(II) complex based on the polypyridyl ligand 2,4,6-tris(2-pyridyl)-1,3,5-triazine (tptz), [Cu(tptz)2]2+: X-ray crystal structure, DNA binding and in vitro cell cytotoxicity

Polyhedron ◽

10.1016/j.poly.2012.06.089 ◽

2012 ◽

Vol 44 (1) ◽

pp. 101-112 ◽

Cited By ~ 60

Author(s):

Khatereh Abdi ◽

Hassan Hadadzadeh ◽

Mona Salimi ◽

Jim Simpson ◽

Aliakbar Dehno Khalaji

Keyword(s):

Crystal Structure ◽

Dna Binding ◽

Cell Cytotoxicity ◽

X Ray ◽

Polypyridyl Ligand

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The Dichloroplatinum(II) Complex of 5,5,7-Trimethyl-1,4-diazacycloheptane: Preparation, Crystal Structure and Binding to Nucleotides and DNA

Australian Journal of Chemistry ◽

10.1071/c97176 ◽

1998 ◽

Vol 51 (11) ◽

pp. 977 ◽

Cited By ~ 5

Author(s):

Chih-Lynne Teo ◽

Ronald R. Fenton ◽

Peter Turner ◽

Trevor W. Hambley

Keyword(s):

Crystal Structure ◽

Dna Binding ◽

Molecular Mechanics ◽

X Ray Diffraction ◽

Binding Studies ◽

Triclinic Space Group ◽

X Ray ◽

Dna Binding Studies ◽

Total Dna ◽

R Value

The preparation of [Pt(tmdz)Cl2] (tmdz = 5,5,7-trimethyl-1,4-diazacycloheptane) is described. The crystal structure has been determined by X-ray diffraction methods and refined to an R value of 0·048 (764F). The crystals are triclinic, space group P -1, a 8·023(2), b 10·874(4), c 14·207(3) Å, α 95·34(3), β 94·96(2), γ 94·97(3)°. N.m.r. studies and molecular mechanics methods show that only one diastereomer of the complex—that observed in the crystal structure—is energetically accessible. In total DNA binding studies, [Pt(tmdz)Cl2] binds less effectively and at a lower rate than cisplatin. The complex reacts with dG and d(GpG) to form a variety of isomeric products, as indicated by h.p.l.c. analysis.

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