C2-symmetric proline-derived tetraamine as highly effective catalyst for direct asymmetric Michael addition of ketones to chalcones

2012 ◽  
Vol 10 (18) ◽  
pp. 3721 ◽  
Author(s):  
Shijun Ma ◽  
Lulu Wu ◽  
Ming Liu ◽  
Yongmei Wang
Keyword(s):  
Michael Addition ◽  
Effective Catalyst ◽  
Asymmetric Michael Addition ◽  
Highly Effective

l-Prolinal Dithioacetal: A Highly Effective Organocatalyst for the Direct Nitro-Michael Addition to Selected Cyclic and Aromatic Ketones

Synthesis ◽  
2019 ◽  
Vol 51 (17) ◽  
pp. 3356-3368
Author(s):  
Piotr Pomarański ◽  
Zbigniew Czarnocki
Keyword(s):  
Michael Addition ◽  
Ring Size ◽  
Cyclic Ketones ◽  
Asymmetric Syntheses ◽  
Aromatic Ketones ◽  
Ring Systems ◽  
Effective Catalyst ◽  
Acetophenone Derivatives ◽  
Highly Effective ◽  
Related Compounds

The synthesis of novel l-prolinal dithioacetal and its application as an organocatalyst for the direct Michael addition of cyclic ketones and acetophenone derivatives to trans-β-nitrostyrene and related compounds is described. The prolinal dithioacetal acts as effective catalyst in the case of cyclic ketones of different ring size, in particular five- and six-membered examples, as well as larger and smaller ring systems. High enantioselectivity and diastereoselectivity is observed for different substrates and trans-β-nitrostyrenes. Also, the first asymmetric syntheses of selected 2-methyl-4-nitro-1,3-diphenylbutan-1-one derivatives by application of the obtained organocatalyst is presented.

Novel pyrrolidine-thiohydantoins/thioxotetrahydropyrimidinones as highly effective catalysts for the asymmetric Michael addition

2011 ◽  
Vol 9 (9) ◽  
pp. 3386 ◽  
Author(s):  
Christoforos G. Kokotos ◽  
Dimitris Limnios ◽  
Despoina Triggidou ◽  
Maria Trifonidou ◽  
George Kokotos
Keyword(s):  
Michael Addition ◽  
Asymmetric Michael Addition ◽  
Highly Effective

ChemInform Abstract: Novel Pyrrolidine-thiohydantoins/thioxotetrahydropyrimidinones as Highly Effective Catalysts for the Asymmetric Michael Addition.

ChemInform ◽  
2011 ◽  
Vol 42 (36) ◽  
pp. no-no
Author(s):  
Christoforos G. Kokotos ◽  
Dimitris Limnios ◽  
Despoina Triggidou ◽  
Maria Trifonidou ◽  
George Kokotos
Keyword(s):  
Michael Addition ◽  
Asymmetric Michael Addition ◽  
Highly Effective

Cross β-alkylation of primary alcohols catalysed by DMF-stabilized iridium nanoparticles

2021 ◽  
Author(s):  
Masaki Kobayashi ◽  
Hiroki Yamaguchi ◽  
Takeyuki Suzuki ◽  
Yasushi Obora
Keyword(s):  
Primary Alcohols ◽  
Recycling Process ◽  
Catalyst Recycling ◽  
Simple Method ◽  
Benzyl Alcohols ◽  
Effective Catalyst ◽  
Iridium Nanoparticles ◽  
Highly Effective ◽  
Linear Alcohols ◽  
The Cross

A simple method for the cross β-alkylation of linear alcohols with benzyl alcohols in the presence of DMF-stabilized iridium nanoparticles was developed. Furthermore, a highly effective catalyst-recycling process was also developed.

Highly Effective Catalyst for the Reaction of Trialkylphosphites with C˭X Electrophiles

2011 ◽  
Vol 186 (4) ◽  
pp. 796-798 ◽  
Author(s):  
Olga O. Kolodiazhna ◽  
Anastasia O. Kolodiazhna ◽  
Oleg I. Kolodiazhnyi
Keyword(s):  
Effective Catalyst ◽  
Highly Effective

Pyrrolidinyl-Camphor Derivatives as a New Class of Organocatalyst for Direct Asymmetric Michael Addition of Aldehydes and Ketones to β-Nitroalkenes

2010 ◽  
Vol 16 (23) ◽  
pp. 7030-7038 ◽  
Author(s):  
Ying-Fang Ting ◽  
Chihliang Chang ◽  
Raju Jannapu Reddy ◽  
Dhananjay R. Magar ◽  
Kwunmin Chen
Keyword(s):  
Michael Addition ◽  
New Class ◽  
Asymmetric Michael Addition ◽  
Aldehydes And Ketones ◽  
Camphor Derivatives

ChemInform Abstract: Asymmetric Michael Addition of Ketones to Nitroolefins: Pyrrolidinyl-oxazole-carboxamides as New Efficient Organocatalysts.

ChemInform ◽  
2015 ◽  
Vol 46 (12) ◽  
pp. no-no
Author(s):  
Ahmed Kamal ◽  
Manda Sathish ◽  
Vunnam Srinivasulu ◽  
Jadala Chetna ◽  
Kunta Chandra Shekar ◽  
...  
Keyword(s):  
Michael Addition ◽  
Asymmetric Michael Addition

scholarly journals Synthesis of new pyrrolidine-based organocatalysts and study of their use in the asymmetric Michael addition of aldehydes to nitroolefins

2017 ◽  
Vol 13 ◽  
pp. 612-619 ◽  
Author(s):  
Alejandro Castán ◽  
Ramón Badorrey ◽  
José A Gálvez ◽  
María D Díaz-de-Villegas
Keyword(s):  
Michael Addition ◽  
Bulky Substituent ◽  
Asymmetric Michael Addition ◽  
Iodination Reaction ◽  
Chiral Imines ◽  
New Compounds ◽  
The Michael Addition

New pyrrolidine-based organocatalysts with a bulky substituent at C2 were synthesized from chiral imines derived from (R)-glyceraldehyde acetonide by diastereoselective allylation followed by a sequential hydrozirconation/iodination reaction. The new compounds were found to be effective organocatalysts for the Michael addition of aldehydes to nitroolefins and enantioselectivities up to 85% ee were achieved.

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