Design, synthesis and evaluation of novel tacrine–rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease

Su-Yi Li; Neng Jiang; Sai-Sai Xie; Kelvin D. G. Wang; Xiao-Bing Wang; Ling-Yi Kong

doi:10.1039/c3ob42010h

Design, synthesis and evaluation of novel tacrine–rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease

Organic & Biomolecular Chemistry ◽

10.1039/c3ob42010h ◽

2014 ◽

Vol 12 (5) ◽

pp. 801-814 ◽

Cited By ~ 56

Author(s):

Su-Yi Li ◽

Neng Jiang ◽

Sai-Sai Xie ◽

Kelvin D. G. Wang ◽

Xiao-Bing Wang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Design Synthesis ◽

Multifunctional Agents

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Phthalimide‐(N‐alkylbenzylamine) cysteamide hybrids as multifunctional agents against Alzheimer’s disease: Design, synthesis and biological evaluation

Chemical Biology & Drug Design ◽

10.1111/cbdd.13905 ◽

2021 ◽

Author(s):

Heng Zhang ◽

Qing Song ◽

Guangjun Yu ◽

Zhongcheng Cao ◽

Xiaoming Qiang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis and evaluation of novel dimethylamino chalcone-O-alkylamines derivatives as potential multifunctional agents against Alzheimer’s disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113310 ◽

2021 ◽

Vol 216 ◽

pp. 113310

Author(s):

Zhipei Sang ◽

Qing Song ◽

Zhongcheng Cao ◽

Yong Deng ◽

Zhenghuai Tan ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Design Synthesis ◽

Multifunctional Agents

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Design, synthesis and evaluation of novel ferulic acid- O -alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.02.039 ◽

2017 ◽

Vol 130 ◽

pp. 379-392 ◽

Cited By ~ 35

Author(s):

Zhipei Sang ◽

Wanli Pan ◽

Keren Wang ◽

Qinge Ma ◽

Lintao Yu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Ferulic Acid ◽

Design Synthesis ◽

Multifunctional Agents

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Design, synthesis and evaluation of novel bivalent β -carboline derivatives as multifunctional agents for the treatment of Alzheimer's disease

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2018.06.018 ◽

2018 ◽

Vol 26 (13) ◽

pp. 3812-3824 ◽

Cited By ~ 8

Author(s):

Yifan Zhao ◽

Feng Ye ◽

Jian Xu ◽

Qinghong Liao ◽

Lei Chen ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Design Synthesis ◽

Multifunctional Agents

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Design, synthesis, and evaluation of isoflavone analogs as multifunctional agents for the treatment of Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.02.053 ◽

2019 ◽

Vol 168 ◽

pp. 207-220 ◽

Cited By ~ 8

Author(s):

Dongmei Wang ◽

Min Hu ◽

Xinpeng Li ◽

Dan Zhang ◽

Chengjuan Chen ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Design Synthesis ◽

Multifunctional Agents

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Design, synthesis and evaluation of chalcone Mannich base derivatives as multifunctional agents for the potential treatment of Alzheimer’s disease

Bioorganic Chemistry ◽

10.1016/j.bioorg.2019.03.043 ◽

2019 ◽

Vol 87 ◽

pp. 395-408 ◽

Cited By ~ 10

Author(s):

Xiaoyu Zhang ◽

Qing Song ◽

Zhongcheng Cao ◽

Yan Li ◽

Chaoquan Tian ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mannich Base ◽

Potential Treatment ◽

Design Synthesis ◽

Multifunctional Agents

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Design, synthesis and biological evaluation of benzylisoquinoline derivatives as multifunctional agents against Alzheimer’s disease

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2014.03.058 ◽

2014 ◽

Vol 24 (10) ◽

pp. 2368-2373 ◽

Cited By ~ 5

Author(s):

Zi-Chen Xu ◽

Xiao-Bing Wang ◽

Wen-Ying Yu ◽

Sai-Sai Xie ◽

Su-Yi Li ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of 2-acetyl-5- O -(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer’s disease

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2017.09.057 ◽

2017 ◽

Vol 27 (22) ◽

pp. 5046-5052 ◽

Cited By ~ 9

Author(s):

Zhipei Sang ◽

Keren Wang ◽

Huifang Wang ◽

Huijuan Wang ◽

Qianwen Ma ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Alkyl Phenol ◽

Phenol Derivatives ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of Schiff’s base derivatives as multifunctional agents for the treatment of Alzheimer’s disease

Medicinal Chemistry Research ◽

10.1007/s00044-020-02666-6 ◽

2020 ◽

Author(s):

Jian Shi ◽

Yi Zhou ◽

Keren Wang ◽

Qinge Ma ◽

Rongrui Wei ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Schiff’S Base ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.114044 ◽

2021 ◽

pp. 114044

Author(s):

Dan Liu ◽

Honghua Zhang ◽

Yuying Wang ◽

Wencheng Liu ◽

Gaofeng Yin ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation ◽

Derivatives Of

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