One-pot synthesis of 6,11-dihydro-5H-indolizino[8,7-b]indoles via sequential formation of β-enamino ester, Michael addition and Pictet–Spengler reactions

RSC Advances ◽  
2014 ◽  
Vol 4 (108) ◽  
pp. 62817-62826 ◽  
Author(s):  
Dan Zhu ◽  
Jing Sun ◽  
Chao-Guo Yan

One pot sequential reaction of generation of β-enamino ester, Michael addition and Pictet–Spengler reaction.

Synlett ◽  
2018 ◽  
Vol 29 (12) ◽  
pp. 1589-1592 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Mahnaz Saraei ◽  
Reyhaneh Khoeiniha

A high-yielding cyclocondensation of 4-hydroxycoumarin, phenylglyoxal monohydrate, and heteroarylamines proceeds without catalysis, which gives novel functionalized furo[3,2-c]coumarins and heteroarylamino alkylation of coumarin products in acetonitrile under reflux, is reported for the first time. This tandem process involves sequentially an aldol condensation, Michael addition, a ring closure, and dehydration reaction.


2009 ◽  
Vol 351 (1-2) ◽  
pp. 141-146 ◽  
Author(s):  
Yun Shi ◽  
Jing Huang ◽  
Yan-Fang Yang ◽  
Lu-Yong Wu ◽  
Yan-Ning Niu ◽  
...  

2011 ◽  
Vol 50 (40) ◽  
pp. 9382-9385 ◽  
Author(s):  
Silvia Sternativo ◽  
Antonella Calandriello ◽  
Ferdinando Costantino ◽  
Lorenzo Testaferri ◽  
Marcello Tiecco ◽  
...  

2020 ◽  
Vol 56 (62) ◽  
pp. 8826-8829
Author(s):  
Nallappan Sundaravelu ◽  
Govindasamy Sekar

A copper catalyzed three-component synthesis of π-conjugated tetracyclic thiochromeno-quinolinone and thiochromeno-thioflavone was established via oxidative double hetero Michael addition using in situ generated nucleophiles.


2010 ◽  
Vol 46 (19) ◽  
pp. 3357 ◽  
Author(s):  
Lingjuan Zhang ◽  
Xianxiu Xu ◽  
Jing Tan ◽  
Ling Pan ◽  
Wenming Xia ◽  
...  

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