The catalytic asymmetric synthesis of tetrahydropyridazines via inverse electron-demand aza-Diels–Alder reaction of enol ethers with azoalkenes
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A highly efficient catalytic asymmetric IEDDA reaction of azoalkenes with enol ethers is reported. This methodology provides a facile entry to biologically important tetrahydropyridazines in good yield with good to excellent ee.
2014 ◽
Vol 53
(18)
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pp. 4680-4684
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2018 ◽
Vol 83
(15)
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pp. 8679-8687
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2007 ◽
Vol 129
(6)
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pp. 1480-1481
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