Design, synthesis, and evaluation of semi-conservative mono-carbonyl analogs of curcumin as anti-inflammatory agents against lipopolysaccharide-induced acute lung injury

MedChemComm ◽  
2015 ◽  
Vol 6 (8) ◽  
pp. 1544-1553 ◽  
Author(s):  
Lili Dong ◽  
Suqing Zheng ◽  
Yali Zhang ◽  
Xin Jiang ◽  
Jianzhang Wu ◽  
...  

Acute lung injury (ALI), one of a few severe diseases with high mortality, cannot be tackled by any effective therapies so far.

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