Selective and efficient synthesis of trans-arylvinylboronates and trans-hetarylvinylboronates using palladium catalyzed cross-coupling

2017 ◽  
Vol 41 (8) ◽  
pp. 3172-3176 ◽  
Author(s):  
Zhihao Liu ◽  
Wei Wei ◽  
Lu Xiong ◽  
Qiang Feng ◽  
Yaojie Shi ◽  
...  
Keyword(s):  
Cross Coupling ◽  
Efficient Synthesis ◽  
Palladium Catalyzed

A versatile method of palladium catalyzed cross-coupling between pinacol vinylboronate and (het)arylbromides to obtain trans-(het)arylvinylboronates in excellent yields and selectivity.

scholarly journals Synthesis of N-(Hetero)arylconvolvine Derivatives through a Palladium-Catalyzed Buchwald–Hartwig Cross-Coupling

Synthesis ◽  
2019 ◽  
Vol 52 (03) ◽  
pp. 450-458
Author(s):  
Manel Hassine ◽  
Hichem Ben Jannet ◽  
NourEddine Ghermani ◽  
Mouad Alami ◽  
Samir Messaoudi
Keyword(s):  
Cross Coupling ◽  
Efficient Synthesis ◽  
Palladium Catalyzed

The present study describes the isolation of convolvine from the roots of the Tunisian plant Convolvulus dorycnium L. and its synthesis through a four-step sequence starting from tropine. Then, an efficient synthesis of N-(het)aryltropanes derivatives by a sequence of a palladium-catalyzed N-arylationof convolvine has been established. This strategy enabled access to unknown tropane scaffolds of biological interests.

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