Rapid diagnostics of liver steatosis by Raman spectroscopyviafiber optic probe: a pilot study

The Analyst ◽  
2018 ◽  
Vol 143 (19) ◽  
pp. 4723-4731 ◽  
Author(s):  
Marta Z. Pacia ◽  
Krzysztof Czamara ◽  
Magdalena Zebala ◽  
Edyta Kus ◽  
Stefan Chlopicki ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Pilot Study ◽  
Diagnostic Tool ◽  
Fiber Optic ◽  
Liver Steatosis ◽  
Rapid Diagnostics ◽  
Fiber Optic Probes ◽  
Optic Probe ◽  
Rapid Quantification

Raman spectroscopyviafiber optic probes enables assessment of the liver condition and rapid quantification of liver steatosis, thus, this technique has the potential as a diagnostic tool.

scholarly journals Modelling, Design and Validation of Spatially Resolved Reflectance Based Fiber Optic Probe for Epithelial Precancer Diagnostics

2020 ◽  
Vol 10 (24) ◽  
pp. 8836
Author(s):  
Pankaj Singh ◽  
Prabodh Pandey ◽  
Shivam Shukla ◽  
Naren Naik ◽  
Asima Pradhan
Keyword(s):  
Fiber Optic ◽  
Numerical Study ◽  
Fiber Optic Probe ◽  
Scattering Coefficients ◽  
Spatially Resolved ◽  
Fiber Optic Probes ◽  
Diagnosis Of Cancer ◽  
Optic Probe ◽  
In Vivo Diagnosis

Fiber-optic probes are imperative for in-vivo diagnosis of cancer. Depending on the access to a diseased organ and the mutations one aims to sense, the probe designs vary. We carry out a detailed numerical study of the efficacy of the common probe geometries for epithelial cancer characterization based on spatially resolved reflectance data. As per the outcomes of this comparative study, a probe has been manufactured and using Monte Carlo look up table based inversion scheme, the absorption and scattering coefficients of the epithelium mimicking top layer have been recovered from noisy synthetic as well as experimental data.

Axial Transmissive f/1.8 Imaging Raman Spectrograph with Volume-Phase Holographic Filter and Grating

1993 ◽  
Vol 47 (11) ◽  
pp. 1913-1919 ◽  
Author(s):  
David E. Battey ◽  
Joseph B. Slater ◽  
Ronald Wludyka ◽  
Harry Owen ◽  
David M. Pallister ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Spatial Frequency ◽  
Fiber Optic ◽  
High Spatial Frequency ◽  
Laser Line ◽  
Fiber Optic Probe ◽  
Volume Phase ◽  
Transmission Grating ◽  
Rejection Filter ◽  
Optic Probe

An axial transmissive Raman spectrograph is described. The instrument employs volume-phase holograms as the laser line rejection filter and transmission grating. The on-axis configuration and the use of a high-spatial-frequency transmission grating allows nearly diffraction-limited imaging and pixel-limited resolution at f/1.8. The performance of the instrument is demonstrated for fiber-optic probe and microprobe Raman spectroscopy.

Author response for "Rapid quantification of constituents in tobacco by NIR fiber‐optic probe"

2020 ◽  
Author(s):  
Gabrielle Fernanda Zimmer ◽  
Roberta Oliveira Santos ◽  
Iberê Damé Teixeira ◽  
Rosana de Cassia de Souza Schneider ◽  
Gilson Augusto Helfer ◽  
...  
Keyword(s):  
Fiber Optic ◽  
Author Response ◽  
Fiber Optic Probe ◽  
Optic Probe ◽  
Rapid Quantification

scholarly journals Accurate assessment of liver steatosis in animal models using a high throughput Raman fiber optic probe

The Analyst ◽  
2015 ◽  
Vol 140 (19) ◽  
pp. 6602-6609 ◽  
Author(s):  
Kevin C. Hewitt ◽  
Javad Ghassemi Rad ◽  
Hanna C. McGregor ◽  
Erin Brouwers ◽  
Heidi Sapp ◽  
...  
Keyword(s):  
Animal Models ◽  
High Throughput ◽  
Fiber Optic ◽  
Liver Steatosis ◽  
Accurate Assessment ◽  
Fiber Optic Probe ◽  
Probe System ◽  
Hepatic Fat ◽  
Optic Probe ◽  
Biochemical Assessment

A high throughput Raman fiber probe system provides accurate and rapid biochemical assessment of the hepatic fat content of livers.

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