Copper and palladium-catalyzed sequential reactions: one-pot synthesis of isoindolo[2,1-b]isoquinolin-7(5H)-ones

2019 ◽  
Vol 17 (17) ◽  
pp. 4281-4290 ◽  
Author(s):  
Hitesh Kumar Saini ◽  
Shiv Dhiman ◽  
Nitesh Kumar Nandwana ◽  
Rangan Krishnan ◽  
Anil Kumar
Keyword(s):  
Heck Reaction ◽  
Sonogashira Coupling ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Ligand Free ◽  
Palladium Catalyzed ◽  
Sequential Reactions

A highly efficient protocol has been developed for the synthesis of diversely substituted isoindolo[2,1-b]isoquinolin-7(5H)-ones through sequential Cu(ii)-catalyzed Sonogashira coupling, intramolecular hydroamidation followed by palladium-catalyzed ligand free Heck reaction.

Pd-PEPPSI-IPentCl: a new highly efficient ligand-free and recyclable catalyst system for the synthesis of 2-substituted indoles via domino copper-free Sonogashira coupling/cyclization

2017 ◽  
Vol 41 (16) ◽  
pp. 8187-8195 ◽  
Author(s):  
Murali Krishna Kolli ◽  
Nagul Meera Shaik ◽  
Govindasamy Chandrasekar ◽  
Sridhar Chidara ◽  
Raghu Babu Korupolu
Keyword(s):  
Copper Catalyst ◽  
Catalyst System ◽  
Recyclable Catalyst ◽  
Sonogashira Coupling ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Intermolecular Cyclization ◽  
Ligand Free

One pot synthesis of 2-substituted indolesviaSonogashira coupling (without a copper catalyst) followed by intermolecular cyclization using Pd-PEPPSI-IPentCl.

A one-pot synthesis of 2,2′-disubstituted diindolylmethanes (DIMs) via a sequential Sonogashira coupling and cycloisomerization/C3-functionalization of 2-iodoanilines

2017 ◽  
Vol 15 (33) ◽  
pp. 6997-7007 ◽  
Author(s):  
Anirban Kayet ◽  
Vinod K. Singh
Keyword(s):  
Sonogashira Coupling ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis

Pd(ii)–Ag(i) catalysed, highly efficient synthesis of diindolylmethanes under mild reaction conditions, with six new bonds being formed in a one-pot fashion, and the products being transformed into synthetically useful compounds.

Palladium-Catalyzed Heck Coupling-Hydrogenation: Highly Efficient One-Pot Synthesis of Dibenzyls and Alkyl Phenyl Esters

2008 ◽  
Vol 350 (16) ◽  
pp. 2544-2550 ◽  
Author(s):  
M. Lakshmi Kantam ◽  
Rajashree Chakravarti ◽  
Venkat Reddy Chintareddy ◽  
B. Sreedhar ◽  
Suresh Bhargava
Keyword(s):  
Heck Coupling ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Palladium Catalyzed

A Highly Efficient Palladium-Catalyzed One-Pot Synthesis of Unsymmetrical Aryl Alkyl Thioethers under Mild Conditions in Water

2012 ◽  
Vol 354 (5) ◽  
pp. 839-845 ◽  
Author(s):  
Liang Wang ◽  
Wei-You Zhou ◽  
Sheng-Chun Chen ◽  
Ming-Yang He ◽  
Qun Chen
Keyword(s):  
One Pot ◽  
Mild Conditions ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Palladium Catalyzed

One-pot Synthesis of Dibenzofurans via SNAr and Subsequent Ligand-free Palladium-catalyzed Intramolecular Aryl-aryl Cross-coupling Reactions under Microwave Irradiation

2011 ◽  
Vol 66 (8) ◽  
pp. 833-836
Author(s):  
Zhiping Che ◽  
Hui Xu
Keyword(s):  
Microwave Irradiation ◽  
Cross Coupling ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Cross Coupling Reactions ◽  
Ligand Free ◽  
Palladium Catalyzed ◽  
Snar Reaction

An efficient one-pot synthesis of dibenzofurans, via SNAr reaction of aryl halides and ortho-bromophenols in the presence of anhydrous K2CO3 and subsequent ligand-free palladium-catalyzed intramolecular aryl-aryl cross-coupling cyclization under microwave irradiation, is described.

Palladium-Catalyzed Copper-Free Sonogashira Coupling of 2-Bromoarylcarbonyls: Synthesis of Isobenzofurans via One-Pot Reductive Cyclization

Synthesis ◽  
2017 ◽  
Vol 49 (23) ◽  
pp. 5149-5158
Author(s):  
Alavala Krishna Reddy ◽  
Gedu Satyanarayana
Keyword(s):  
Reductive Cyclization ◽  
Sonogashira Coupling ◽  
One Pot ◽  
One Pot Synthesis ◽  
Palladium Catalyzed ◽  
The One

Palladium-catalyzed copper-free Sonogashira coupling of 2-bromocarbonyls is presented. This method afforded the 2-alkynylaryl carbonyls, useful synthons for the accomplishment of many carbocyclic and heterocyclic motifs. Significantly, the strategy was extended to the one-pot synthesis of isobenzofurans via reduction followed by intramolecular 5-exo-dig cyclization.

ChemInform Abstract: A Highly Efficient Palladium-Catalyzed One-Pot Synthesis of Unsymmetrical Aryl Alkyl Thioethers under Mild Conditions in Water.

ChemInform ◽  
2012 ◽  
Vol 43 (33) ◽  
pp. no-no
Author(s):  
Liang Wang ◽  
Wei-You Zhou ◽  
Sheng-Chun Chen ◽  
Ming-Yang He ◽  
Qun Chen
Keyword(s):  
One Pot ◽  
Mild Conditions ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Palladium Catalyzed

ChemInform Abstract: Palladium-Catalyzed Heck Coupling-Hydrogenation: Highly Efficient One-Pot Synthesis of Dibenzyls and Alkyl Phenyl Esters.

ChemInform ◽  
2009 ◽  
Vol 40 (11) ◽  
Author(s):  
M. Lakshmi Kantam ◽  
Rajashree Chakravarti ◽  
Venkat Reddy Chintareddy ◽  
B. Sreedhar ◽  
Suresh Bhargava
Keyword(s):  
Heck Coupling ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Palladium Catalyzed
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