Chichibabin pyridinium synthesis via oxidative decarboxylation of photoexcited α-enamine acids

Chemical Communications ◽

10.1039/d0cc07636h ◽

2021 ◽

Author(s):

Zhiqiang Pan ◽

Fengchi Hu ◽

Di Jiang ◽

Yuchang Liu ◽

Chengfeng Xia

Keyword(s):

Amino Acids ◽

Oxidative Decarboxylation

The photoexcited enamines derived from α-amino acids could undergo an oxidative decarboxylation followed by a Chichibabin cyclization to afford highly substituted pyridiniums.

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Thermally Induced Oxidative Decarboxylation of Copper Complexes of Amino Acids and Formation of Strecker Aldehyde

Journal of Agricultural and Food Chemistry ◽

10.1021/jf502751n ◽

2014 ◽

Vol 62 (33) ◽

pp. 8518-8523 ◽

Cited By ~ 25

Author(s):

Ossanna Nashalian ◽

Varoujan A. Yaylayan

Keyword(s):

Amino Acids ◽

Copper Complexes ◽

Oxidative Decarboxylation ◽

Thermally Induced ◽

Strecker Aldehyde

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ChemInform Abstract: Oxidative Decarboxylation of Cyclic Amino Acids and Dehydrogenation of Cyclic Secondary Amines with Iodosobenzene.

ChemInform ◽

10.1002/chin.198926102 ◽

1989 ◽

Vol 20 (26) ◽

Author(s):

M. OCHIAI ◽

M. INENAGA ◽

Y. NAGAO ◽

R. M. MORIARTY ◽

R. K. VAID ◽

...

Keyword(s):

Amino Acids ◽

Secondary Amines ◽

Oxidative Decarboxylation ◽

Cyclic Amino Acids

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ChemInform Abstract: OXIDATION STUDIES. PART II- KINETICS OF THE OXIDATIVE DECARBOXYLATION OF SOME E AMINO ACIDS BY PEROXY DISULFATE CATALYZED BY SILVER IONS

Chemischer Informationsdienst ◽

10.1002/chin.197614118 ◽

1976 ◽

Vol 7 (14) ◽

pp. no-no

Author(s):

M. G. RAM REDDY ◽

B. SETHURAM ◽

T. NAVANEETH RAO

Keyword(s):

Amino Acids ◽

Silver Ions ◽

Oxidative Decarboxylation ◽

Kinetics Of

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THE DIAGNOSIS OF MAPLE SYRUP URINE DISEASE (Branched-chain Ketoaciduria)

PEDIATRICS ◽

10.1542/peds.32.2.234 ◽

1963 ◽

Vol 32 (2) ◽

pp. 234-238

Author(s):

Joseph Dancis ◽

Joel Hutzler ◽

Mortimer Levitz

Keyword(s):

Amino Acids ◽

Maple Syrup Urine Disease ◽

Oxidative Decarboxylation ◽

Maple Syrup ◽

Peripheral Leukocyte ◽

Metabolic Block ◽

Urine Disease ◽

Branched Chain ◽

Normal Leukocyte

The metabolism of the three branched-chain amino acids has been investigated in vitro, using the peripheral leukocyte. The normal leukocyte can transaminate and decarboxylate the three amino acids. These functions are demonstrable at birth. Five cases of maple syrup urine disease (branched-chain ketoaciduria) were studied. The peripheral leukocyte could transaminate the three amino acids, but decarboxylation was greatly reduced or absent. This confirms the site of metabolic block in maple syrup urine disease, and suggests an early and specific approach to diagnosis. Oxidative-decarboxylation of the branched-chain ketoacids involves an enzyme common to all three ketoacids.

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