MCR-ALS with Sample Insertion Constraint to Enhance the Sensitivity of Surface-Enhanced Raman Scattering Detection

The Analyst ◽  
2021 ◽  
Author(s):  
Nontawat Sricharoen ◽  
Thanyada Sukmanee ◽  
Prompong Pienpinijtham ◽  
Sanong Ekgasit ◽  
Yasutaka Kitahama ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Least Square ◽  
Multivariate Curve Resolution ◽  
Curve Resolution ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Overlapping Peaks ◽  
Als Algorithm

The multivariate curve resolution-alternative least square (MCR-ALS) algorithm was modified with sample insertion constraint to deconvolute the overlapping peaks in SERS spectra. The developed method was evaluated by the spectral...

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