BF3.OEt2 Catalyzed Synthesis of Functionalized 9-fluorene-9-ylidene Appended Quinazolin-4-ones

New Journal of Chemistry ◽

10.1039/d1nj05379e ◽

2022 ◽

Author(s):

Mohanakumaran Athira ◽

Snoxma Smile Suresh ◽

Ponnusamy Shanmugam

Keyword(s):

Efficient Method ◽

Boron Trifluoride

An efficient method for the construction of the quinazolinone skeleton from the reaction of 9-(phenylethynyl)-9H-fluoren-9-ols with substituted 2-aminobenzamides catalyzed by boron trifluoride is achieved. Scope of the reaction with a...

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Polyvinylpolypyrrolidone-Supported Boron Trifluoride; Highly Efficient Catalyst for the Synthesis ofN-tert-Butyl Amides

E-Journal of Chemistry ◽

10.1155/2012/632574 ◽

2012 ◽

Vol 9 (2) ◽

pp. 576-582 ◽

Cited By ~ 6

Author(s):

Masoud Mokhtary ◽

Faranak Najafizadeh

Keyword(s):

Lewis Acid ◽

Efficient Method ◽

Boron Trifluoride ◽

Butyl Acetate ◽

Acid Property ◽

Solid Catalyst ◽

Efficient Catalyst ◽

Tert Butyl ◽

Highly Efficient ◽

Boron Trifluoride Complex

Highly efficient method for the preparation ofN-tert-butyl amides by reaction of nitriles withtert-butyl acetate is described using polyvinylpolypyrrolidone-supported boron trifluoride (PVPP-BF3) at 70°C in good to excellent yields. Selective amidation of benzonitrile in the presence of acetonitrile was also achieved. polyvinylpolypyrrolidone-boron trifluoride complex shows non-corrosive and stable solid catalyst elevated Lewis acid property.

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Insect Moulting Hormones. LV. Experiments Directed Towards the Synthesis of Non-steroidal Ecdysone Analogues

Australian Journal of Chemistry ◽

10.1071/ch9850475 ◽

1985 ◽

Vol 38 (3) ◽

pp. 475 ◽

Cited By ~ 3

Author(s):

R Bergamasco ◽

DHS Horn ◽

RH Nearn ◽

JS Wilkie

Keyword(s):

Efficient Method ◽

Boron Trifluoride ◽

Model Compound ◽

Boron Trifluoride Etherate ◽

Side Chain ◽

Mercuric Oxide ◽

Moulting Hormones

Exploratory studies aimed at the synthesis of the non-steroidal ecdysone analogue (4aR,7S,8aR,-1′RS,4′R)-7-hydroxy-3-(1′-hydroxy-4′,8′- dimethylnonyl )-4a-methyl-4a,5,6,7,8,8a-hexahydronaphthal-en- 1(4H)-one (3) have led to in efficient method of joining the cyclic and side-chain synthons by reacting the vinylogous ester (4a) with 1-lithio-4,8-dimethyl-1,1-bis( methylthio ) nonane (12) to yield (4′RS)-3- [4′,8′-dimethyl-1′,1′-bis( methylthio ) nonyl ]-5,5-dimethylcyclohex-2-en-1-one (13). This thioacetal on reaction with boron trifluoride etherate and mercuric oxide afforded, quantitatively, the diketone (4′RS)-3-(4′,8′-dimethyl-1′-oxononyl)-5,5-dimethylcyclohex-2-en-1-one (14) which was selectively reduced in 85% yield to the required model compound (4′RS)-3-(1′-hydroxy-4′,8′-dimethylnonyl)-5,5-dimethylcyclohex-2-en-1-one (15).

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