Multicomponent Cascade Reaction of HKAs: Synthesis of Highly Functionalized 5H-Chromeno[4,3-d]pyrimidines

2021 ◽  
Author(s):  
Sheng-Jiao Yan ◽  
Yun-Xiang Fan ◽  
Xin-Ling Cao ◽  
Li Chen ◽  
Yi-Hua Chen
Keyword(s):  
Ring Opening ◽  
Cascade Reaction ◽  
Ketene Aminals

A novel protocol was developed for the construction of highly functionalized 5H-Chromeno[4,3-d]pyrimidines (CMPDs) from 3-formylchromones, heterocyclic ketene aminals and amidine hydrochlorides via an unprecedented cascade reaction involving the interesting ring-opening...

Cut and sew: benzofuran-ring-opening enabled cyclopentenone ring formation

2020 ◽  
Vol 56 (84) ◽  
pp. 12817-12820
Author(s):  
Kai Wang ◽  
Chenghao Jiang ◽  
Zhenming Zhang ◽  
Chunyu Han ◽  
Xuewei Wang ◽  
...  
Keyword(s):  
Ring Opening ◽  
Cascade Reaction ◽  
Ring Formation ◽  
Acid Catalyzed

A broad range of fully substituted cyclopentenones are constructed efficiently via an acid catalyzed cascade reaction involving an unprecedented benzofuran-ring-opening.

ChemInform Abstract: Zeo-Click Chemistry: Copper(I)-Zeolite-Catalyzed Cascade Reaction: One-Pot Epoxide Ring-Opening and Cycloaddition.

ChemInform ◽  
2011 ◽  
Vol 42 (15) ◽  
pp. no-no
Author(s):  
Thirupathi Boningari ◽  
Andrea Olmos ◽  
Benjaram M. Reddy ◽  
Jean Sommer ◽  
Patrick Pale
Keyword(s):  
Click Chemistry ◽  
Ring Opening ◽  
Cascade Reaction ◽  
Epoxide Ring ◽  
One Pot ◽  
Epoxide Ring Opening

Synthesis of Polycyclic Spiroindolines via the Cascade Reaction of 3-(2-isocyanoethyl)Indoles

2021 ◽  
Author(s):  
Haizhen Li ◽  
Jinyu Wu ◽  
Jianfeng Zheng ◽  
Wei-Dong Z. Li
Keyword(s):  
Ring Opening ◽  
Cascade Reaction ◽  
Tandem Reactions ◽  
Ring Opening Reaction

Tandem reactions of Yttrium(III) catalyzed ring-opening reaction of 2,2’-diester aziridines with 3-(2-isocyanoethyl)indoles and subsequent Friedel-Crafts/Mannich/desulfonylation were reported. A series of polycyclic spiroindolines containing tetrahydro-β-carbonlines were obtained in moderate to excellent...

A cascade reaction: ring-opening insertion of dioxaphospholane into lutetium alkyl bonds

2014 ◽  
Vol 43 (6) ◽  
pp. 2448-2457 ◽  
Author(s):  
Kevin R. D. Johnson ◽  
Paul G. Hayes
Keyword(s):  
Ring Opening ◽  
Cascade Reaction ◽  
Insertion Reaction ◽  
Pincer Ligand

Although an organolutetium complex of a new dioxaphospholane-substituted carbazole-based pincer ligand appears immune to cyclometalation, an unusual ring-opening insertion reaction was observed.

A Route to Highly Functionalized Stereospecific trans-Aminated Aurones from 3-Bromoflavones with Aniline and N-Phenylurea via a Domino Aza-Michael Ring Opening and Cyclization Reactions

Synthesis ◽  
2018 ◽  
Vol 51 (04) ◽  
pp. 960-970 ◽  
Author(s):  
Naseem Ahmed ◽  
Iram Parveen
Keyword(s):  
Michael Addition ◽  
Ring Opening ◽  
Cascade Reaction ◽  
Cyclization Reactions ◽  
Reaction Conditions ◽  
Aniline Derivatives

A facile cascade reaction is reported via aza-Michael addition, ring opening, and cyclization between 3-bromoflavone and aniline derivatives or N-phenylurea in the presence of KOt-Bu and CuI in DMF under mild reaction conditions. Products were obtained as stereospecific trans-aminated aurones in good to excellent yields (61–83%). Our protocol is operationally successful with ease, avoids the requirement of additives and ligands, and offers broad substrate scope.

Zeo-Click Chemistry: Copper(I)-Zeolite-Catalyzed Cascade Reaction; One-Pot Epoxide Ring-Opening and Cycloaddition

2010 ◽  
Vol 2010 (33) ◽  
pp. 6338-6347 ◽  
Author(s):  
Thirupathi Boningari ◽  
Andrea Olmos ◽  
Benjaram M. Reddy ◽  
Jean Sommer ◽  
Patrick Pale
Keyword(s):  
Click Chemistry ◽  
Ring Opening ◽  
Cascade Reaction ◽  
Epoxide Ring ◽  
One Pot ◽  
Epoxide Ring Opening

scholarly journals An efficient synthesis of new imidazo[1,2-a]pyridine-6-carbohydrazide and pyrido[1,2-a]pyrimidine-7-carbohydrazide derivatives via a five-component cascade reaction

RSC Advances ◽  
2019 ◽  
Vol 9 (13) ◽  
pp. 7218-7227 ◽  
Author(s):  
Hajar Hosseini ◽  
Mohammad Bayat
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Ketene Aminals

An easy synthesis of novel and highly substituted imidazo[1,2-a]pyridines and pyrido[1,2-a]pyrimidines using heterocyclic ketene aminals.

ChemInform Abstract: Catalyst-Free Cascade Reaction of Heterocyclic Ketene Aminals with N-Substituted Maleimide to Synthesise Bicyclic Pyrrolidinone Derivatives.

ChemInform ◽  
2015 ◽  
Vol 46 (6) ◽  
pp. no-no
Author(s):  
Jin Liu ◽  
Hai-Rui Zhang ◽  
Xin-Rong Lin ◽  
Sheng-Jiao Yan ◽  
Jun Lin
Keyword(s):  
Cascade Reaction ◽  
Catalyst Free ◽  
Ketene Aminals
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