scholarly journals Scalable synthesis of favipiravir via conventional and continuous flow chemistry

RSC Advances ◽  
2021 ◽  
Vol 11 (61) ◽  
pp. 38691-38693
Author(s):  
Thanat Tiyasakulchai ◽  
Netnapa Charoensetakul ◽  
Thitiphong Khamkhenshorngphanuch ◽  
Chawanee Thongpanchang ◽  
Onsiri Srikun ◽  
...  

Decagram scale synthesis of favipiravir was performed in 9 steps using diethyl malonate as cheap starting material.

Author(s):  
Jessica Orrego‐Hernández ◽  
Helen Hölzel ◽  
Maria Quant ◽  
Zhihang Wang ◽  
Kasper Moth‐Poulsen

Author(s):  
Jessica Orrego-Hernández ◽  
Helen Hölzel ◽  
Maria Quant ◽  
Zhihang Wang ◽  
Kasper Moth-Poulsen

Author(s):  
Nicole Candice Neyt ◽  
Darren Lyall Riley

The adoption of flow technology for the manufacture of chemical entities, and in particular pharmaceuticals, has seen rapid growth over the past two decades with the technology now blurring the...


2017 ◽  
Vol 7 (3–4) ◽  
pp. 157-158 ◽  
Author(s):  
Daniel Blanco-Ania ◽  
Floris P. J. T. Rutjes

ChemInform ◽  
2014 ◽  
Vol 45 (44) ◽  
pp. no-no
Author(s):  
Jan Hartwig ◽  
Jan B. Metternich ◽  
Nikzad Nikbin ◽  
Andreas Kirschning ◽  
Steven V. Ley

Author(s):  
Cloudius Sagandira ◽  
Sinazo Nqeketo ◽  
Kanysile Mhlana ◽  
Thembela Sonti ◽  
Paul Watts ◽  
...  

Continuous flow chemistry has opened a new paradigm in both the laboratory and pharmaceutical industry. This review details the recently reported literature on continuous multistep telescoped synthesis of active pharmaceutical...


2021 ◽  
pp. 145-178
Author(s):  
Kian Donnelly ◽  
Mara Di Filippo ◽  
Cormac Bracken ◽  
Marcus Baumann

Sign in / Sign up

Export Citation Format

Share Document