Plasma Volume and Extracellular Fluid Volume during Long-Term Treatment with Propranolol in Essential Hypertension

1972 ◽  
Vol 43 (2) ◽  
pp. 165-170 ◽  
Author(s):  
P. Sederberg-Olsen ◽  
H. Ibsen

1. In ten patients with essential hypertension treated with propranolol (320 mg daily for 4 months) plasma volume and extracellular fluid volume were determined. 2. A significant increase in extracellular fluid volume (ECFV) was found, but there was no significant change in plasma volume. 3. The genesis of the increase found in ECFV is briefly discussed.

1973 ◽  
Vol 45 (s1) ◽  
pp. 283s-286s ◽  
Author(s):  
M. A. D. H. Schalekamp ◽  
X. H. Krauss ◽  
G. Kolsters ◽  
M. P. A. Schalekamp ◽  
W. H. Birkenhäger

1. In patients with essential hypertension plasma renin concentration (PRC) was assessed in relation to age, plasma volume, extracellular fluid volume, aldosterone secretion rate, renal vascular resistance, filtration fraction and excess sodium excretion after acute salt loading. 2. Up to a calculated renal vascular resistance of 20 000 dyn s cm−5, PRC was found to be inversely related with the above-mentioned variables except plasma volume, extracellular fluid volume and aldosterone secretion rate. 3. It is concluded that the phenomenon of renin suppression is not dependent on mineralocorticoid excess. Instead, a decrease in PRC together with hypernatriuresis appears to reflect a progressive switch in intrarenal haemodynamic relationships. Renin suppression should therefore be considered to be a feature of progressive, but still uncomplicated, essential hypertension.


1978 ◽  
Vol 28 ◽  
pp. 179
Author(s):  
Toshiaki Kadokawa ◽  
Kanno Hosoki ◽  
Kunihiko Takeyama ◽  
Hisao Minato ◽  
Masanao Shimizu

Author(s):  
M. Carnovali ◽  
C. Borgnino ◽  
E. Crespi ◽  
M. Panozzo ◽  
A. Missaglia ◽  
...  

2009 ◽  
Vol 209 (S646) ◽  
pp. 123-126
Author(s):  
H. Løken ◽  
H. & Hebnes ◽  
K. Diakonissesykehus

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