Dichloromethylene Diphosphonate (Cl2MDP) as an Inhibitor of Bone Resorption in Paget's Disease of Bone

1980 ◽  
Vol 58 (2) ◽  
pp. 24P-24P
Author(s):  
D. L. Douglas ◽  
T. Duckworth ◽  
J. A. Kanis ◽  
C. J. Preston ◽  
J. S. Woodhead ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Paget's Disease Of Bone ◽  
Dichloromethylene Diphosphonate

Long Term Effects of Dichloromethylene Diphosphonate in Paget's Disease of Bone

1982 ◽  
Vol 54 (4) ◽  
pp. 837-844 ◽  
Author(s):  
PIERRE D. DELMAS ◽  
M. C. CHAPUY ◽  
E. VIGNON ◽  
S. CHARHON ◽  
D. BRIANCON ◽  
...  
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Paget's Disease Of Bone ◽  
Long Term Effects ◽  
Dichloromethylene Diphosphonate

The Therapeutic Uses of Calcitonin

1978 ◽  
Vol 23 (2) ◽  
pp. 161-165 ◽  
Author(s):  
T. J. Martin
Keyword(s):  
Bone Resorption ◽  
Therapeutic Effect ◽  
Salmon Calcitonin ◽  
Bone Pain ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Paget's Disease Of Bone ◽  
Therapeutic Uses ◽  
Histological Improvement

Calcitonin is a potent hormonal inhibitor of bone resorption. Its major therapeutic effect is in the treatment of Paget's Disease of bone, in which it has been shown to reduce bone pain, lead to radiological and histological improvement in bone, and to restore abnormal biochemistry towards normal. Some patients are resistant to treatment, and in others resistance may develop during treatment. Although antibodies to pig or to salmon calcitonin develop in almost 50 per cent of treated patients it is only very rarely that resistance may be ascribed to antibodies. There are a number of other clinical states of increased resorption in which the value of calcitonin therapy has yet to be established.

Urinary collagen crosslink excretion: a better index of bone resorption than hydroxyproline in Paget's disease of bone?

1993 ◽  
Vol 22 (1) ◽  
pp. 1-8 ◽  
Author(s):  
N.A.T. Hamdy ◽  
S.E. Papapoulos ◽  
A. Colwell ◽  
R. Eastell ◽  
R.G.G. Russell
Keyword(s):  
Bone Resorption ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Paget's Disease Of Bone

scholarly journals NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone

Bone ◽  
2017 ◽  
Vol 101 ◽  
pp. 236-244 ◽  
Author(s):  
Yuvaraj Sambandam ◽  
Kumaran Sundaram ◽  
Takamitsu Saigusa ◽  
Sundaravadivel Balasubramanian ◽  
Sakamuri V. Reddy
Keyword(s):  
Bone Resorption ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Osteoclast Formation ◽  
Paget’S Disease Of Bone ◽  
Paget's Disease Of Bone

EFFECTS OF DISODIUM DICHLOROMETHYLENE DIPHOSPHONATE ON PAGET'S DISEASE OF BONE

The Lancet ◽  
1979 ◽  
Vol 314 (8141) ◽  
pp. 489-492 ◽  
Author(s):  
P.J. Meunier ◽  
C. Alexandre ◽  
C. Edouard ◽  
L. Mathieu ◽  
M.C. Chapuy ◽  
...  
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Paget's Disease Of Bone ◽  
Dichloromethylene Diphosphonate

Biochemical and clinical responses to dichloromethylene diphosphonate (cl2mdp) in paget's disease of bone

1980 ◽  
Vol 23 (10) ◽  
pp. 1185-1192 ◽  
Author(s):  
D. L. Douglas ◽  
T. Duckworth ◽  
J. A. Kanis ◽  
C. Preston ◽  
D. J. Beard ◽  
...  
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Paget’S Disease Of Bone ◽  
Paget's Disease Of Bone ◽  
Dichloromethylene Diphosphonate ◽  
Clinical Responses
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