Mutant superoxide dismutase 1 causes motor neuron degeneration independent of cyclin-dependent kinase 5 activation by p35 or p25

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2003.02256.x ◽

2004 ◽

Vol 88 (5) ◽

pp. 1295-1304 ◽

Author(s):

Satoru Takahashi ◽

Ashok B. Kulkarni

Keyword(s):

Superoxide Dismutase ◽

Motor Neuron ◽

Superoxide Dismutase 1 ◽

Cyclin Dependent Kinase ◽

Motor Neuron Degeneration ◽

Neuron Degeneration ◽

Cyclin Dependent Kinase 5

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Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: Mechanisms of mitochondriopathy and cell death

The Journal of Comparative Neurology ◽

10.1002/cne.21160 ◽

2006 ◽

Vol 500 (1) ◽

pp. 20-46 ◽

Author(s):

Lee J. Martin ◽

Zhiping Liu ◽

Kevin Chen ◽

Ann C. Price ◽

Yan Pan ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Transgenic Mice ◽

Motor Neuron ◽

Superoxide Dismutase 1 ◽

Motor Neuron Degeneration ◽

Neuron Degeneration ◽

Lateral Sclerosis

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Spinal Inhibitory Interneuron Pathology Follows Motor Neuron Degeneration Independent of Glial Mutant Superoxide Dismutase 1 Expression in SOD1-ALS Mice

Journal of Neuropathology & Experimental Neurology ◽

10.1097/nen.0b013e31822581ac ◽

2011 ◽

Vol 70 (8) ◽

pp. 662-677 ◽

Author(s):

Mehdi Hossaini ◽

Sebastian Cardona Cano ◽

Vera van Dis ◽

Elize D. Haasdijk ◽

Casper C. Hoogenraad ◽

...

Keyword(s):

Superoxide Dismutase ◽

Motor Neuron ◽

Inhibitory Interneuron ◽

Superoxide Dismutase 1 ◽

Motor Neuron Degeneration ◽

Neuron Degeneration

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Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1103141108 ◽

2011 ◽

Vol 108 (43) ◽

pp. 17803-17808 ◽

Author(s):

S. T. Papadeas ◽

S. E. Kraig ◽

C. O'Banion ◽

A. C. Lepore ◽

N. J. Maragakis

Keyword(s):

Superoxide Dismutase ◽

Motor Neuron ◽

Superoxide Dismutase 1 ◽

Wild Type ◽

Motor Neuron Degeneration ◽

Neuron Degeneration ◽

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Non-Aggregating Tau Phosphorylation by Cyclin-Dependent Kinase 5 Contributes to Motor Neuron Degeneration in Spinal Muscular Atrophy

Journal of Neuroscience ◽

10.1523/jneurosci.3716-14.2015 ◽

2015 ◽

Vol 35 (15) ◽

pp. 6038-6050 ◽

Author(s):

Nimrod Miller ◽

Zhihua Feng ◽

Brittany M. Edens ◽

Ben Yang ◽

Han Shi ◽

...

Keyword(s):

Spinal Muscular Atrophy ◽

Motor Neuron ◽

Muscular Atrophy ◽

Tau Phosphorylation ◽

Cyclin Dependent Kinase ◽

Motor Neuron Degeneration ◽

Neuron Degeneration ◽

Cyclin Dependent Kinase 5

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Fibrillar Inclusions and Motor Neuron Degeneration in Transgenic Mice Expressing Superoxide Dismutase 1 with a Disrupted Copper-Binding Site

Neurobiology of Disease ◽

10.1006/nbdi.2002.0498 ◽

2002 ◽

Vol 10 (2) ◽

pp. 128-138 ◽

Author(s):

Jiou Wang ◽

Guilian Xu ◽

Victoria Gonzales ◽

Michael Coonfield ◽

David Fromholt ◽

...

Keyword(s):

Superoxide Dismutase ◽

Transgenic Mice ◽

Motor Neuron ◽

Binding Site ◽

Copper Binding ◽

Superoxide Dismutase 1 ◽

Motor Neuron Degeneration ◽

Neuron Degeneration

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Mutant Mice, Cu,Zn Superoxide Dismutase, and Motor Neuron Degeneration

Science ◽

10.1126/science.266.5190.1586-a ◽

1994 ◽

Vol 266 (5190) ◽

pp. 1586-1587 ◽

Author(s):

J. M. McCord

Keyword(s):

Superoxide Dismutase ◽

Motor Neuron ◽

Mutant Mice ◽

Motor Neuron Degeneration ◽

Neuron Degeneration

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Ablation of Proliferating Microglia Does Not Affect Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis Caused by Mutant Superoxide Dismutase

Journal of Neuroscience ◽

10.1523/jneurosci.3494-08.2008 ◽

2008 ◽

Vol 28 (41) ◽

pp. 10234-10244 ◽

Author(s):

G. Gowing ◽

T. Philips ◽

B. Van Wijmeersch ◽

J.-N. Audet ◽

M. Dewil ◽

...

Keyword(s):

Amyotrophic Lateral Sclerosis ◽

Superoxide Dismutase ◽

Motor Neuron ◽

Motor Neuron Degeneration ◽

Neuron Degeneration ◽

Lateral Sclerosis

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

Science ◽

10.1126/science.8209258 ◽

1994 ◽

Vol 264 (5166) ◽

pp. 1772-1775 ◽

Cited By ~ 2694

Author(s):

M. Gurney ◽

H Pu ◽

A. Chiu ◽

M. Dal Canto ◽

C. Polchow ◽

...

Keyword(s):

Superoxide Dismutase ◽

Motor Neuron ◽

Motor Neuron Degeneration ◽

Neuron Degeneration

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Mutant mice, Cu,Zn superoxide dismutase, and motor neuron degeneration

Science ◽

10.1126/science.7985031 ◽

1994 ◽

Vol 266 (5190) ◽

pp. 1586-1586 ◽

Author(s):

J. McCord

Keyword(s):

Superoxide Dismutase ◽

Motor Neuron ◽

Mutant Mice ◽

Motor Neuron Degeneration ◽

Neuron Degeneration

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Faculty Opinions recommendation of Mutations in dynein link motor neuron degeneration to defects in retrograde transport.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013389.190305 ◽

2003 ◽

Author(s):

Mark Bothwell

Keyword(s):

Motor Neuron ◽

Retrograde Transport ◽

Motor Neuron Degeneration ◽

Neuron Degeneration

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