scholarly journals Drug-induced oral mucous membrane pemphigoid: a case report

2017 ◽  
Vol 23 (4) ◽  
pp. 181-183 ◽  
Author(s):  
Bastien Bercault ◽  
Mathilde Fenelon ◽  
Sylvain Catros ◽  
Jean-Marie Marteau ◽  
Jean-Christophe Fricain



Author(s):  
Narjes Akbari ◽  
Ghazaleh Mozafari ◽  
Hamid Abbaszadeh

Mucous membrane pemphigoid (MMP) is a rare inflammatory, autoimmune, and subepithelial vesiculobullous disease in which tissue-bound autoantibodies are produced against one or more components of the basement membrane. Oral lesions of the pemphigoid begin in the form of vesicles or bullae that often involve throughout the mouth but may be confined to specific areas, especially the gingiva, in a pattern known as desquamative gingivitis. The positive Nikolsky's sign is characteristic of pemphigus vulgaris, in which a blister can appear on the normal-appearing skin if exerting lateral pressure, and is very rare in the mucosa and other vesiculobullous diseases. Here we report a case of mucous membrane pemphigoid that developed as desquamated gingivitis in a 46-year-old woman with positive Nikolsky's sign in the gingival mucosa. In the histopathologic view, a subepithelial cleft was observed. The results of direct and indirect immunofluorescence tests and related therapeutic interventions are also presented. Positive Nikolsky's sign can be observed in the mucosa as well as in the mucous membrane pemphigoid in addition to pemphigus vulgaris, and vesiculobullous lesions should be diagnosed based on the sum of clinical, histopathological, and immunofluorescence findings.



2014 ◽  
Vol 24 (2) ◽  
pp. 179 ◽  
Author(s):  
AP Singh ◽  
TR Chaitra ◽  
TL Ravishankar ◽  
SP Singh ◽  
AK Mohapatra


2012 ◽  
Vol 6 (1) ◽  
Author(s):  
Patnarin Kanjanabuch ◽  
Samornroj Arporniem ◽  
Suparat Thamrat ◽  
Pannipa Thumasombut


2006 ◽  
Vol 86 (4) ◽  
pp. 351-354 ◽  
Author(s):  
SV Lourenço ◽  
P Boggio ◽  
LE Martins ◽  
CG Santi ◽  
V Aoki ◽  
...  


Folia Medica ◽  
2020 ◽  
Vol 62 (4) ◽  
pp. 866-870
Author(s):  
Liliya Kavlakova ◽  
Svitlana Bachurska

Mucous membrane pemphigoid (MMP) is a chronic, autoimmune, subepithelial vesiculobullous disease that very frequently affects the mucous membranes and less often the skin. Oral cavity is the most commonly affected site and desquamative gingivitis (DG) is the most common manifestation. This is the main reason why dentists play a vital role in the diagnosis and managing the oral health of patients. Treatment is usually challenging, however, it only can achieve temporary symptomatic effect. We report a case of desquamative gingivi-tis, manifestation of MMP that was treated successfully with topical corticosteroid. The latter was applied by using of individual made custom trays to improve clinical efficacy. 



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