scholarly journals The Atrial Pacing Peri-ablation for Paroxysmal Atrial Fibrillation (PA3) Study

EP Europace ◽  
1999 ◽  
Vol 1 (1) ◽  
pp. 40-42 ◽  
Author(s):  
A. M. Gillis

Abstract The Canadian Atrial Pacing Peri-Ablation for Paroxysmal Atrial Fibrillation Study tested the hypotheses that atrial pacing prevents paroxysmal atrial fibrillation (PAF) in patients without symptomatic bradycardia and that DDDR pacing is more likely to prevent PAF following total atrioventricular (AV) node ablation compared to VDD pacing. Patients with PAF who were refractory to or intolerant of antiarrhythmic drug therapy received a Medtronic Thera DR pacemaker 3 months prior to a planned total AV node ablation. Patients were randomized to atrial pacing or no pacing therapy. The time to first recurrence of sustained PAF was the primary study outcome event. Following AV node ablation, patients were randomized to the DDDR or VDD mode in a crossover study design. Patients were followed in each mode for 6 months. The time course of PAF recurrence was compared for each pacing mode.

2005 ◽  
Vol 62 (4) ◽  
pp. 329-334
Author(s):  
Goran Radjen ◽  
Sasa Rafajlovski ◽  
Zoran Perisic ◽  
Radoslav Romanovic

Background. Atrial fibrillation is the most frequent cardiac dysrhythmia. The aim of this study was to show the role and the efficacy of a dual chamber pacemaker with the algorithm of atrial dynamic overdrive, in the suppression of paroxysmal atrial fibrillation. Case report. A woman with a classical bradycardia-tachycardia syndrome, and frequent attacks of atrial fibrillation, underwent the implantation of a single chamber permanent pacemaker (VVI). Pacemaker successfully treated the episodes of symptomatic bradycardia, but the patient had frequent attacks of atrial fibrillation, despite the use of different antiarrhythmic drugs, which she did not tolerate well. The decision was made to reimplant a permanent dual chamber pacemaker with the algorithm of atrial dynamic overdrive. The pacemaker was programmed to the basic rate of 75/min, while rate at rest was 55/min. In addition, sotalol was administered. After three months, the patient became asymptomatic with only 4 short ? term episodes of atrial fibrillation, and a high level of atrial pacing (99%). Conclusion. In selected patients with bradycardia?tachycardia syndrome, atrial-based pacing seemed to be very effective in reducing the incidence of paroxysmal atrial fibrillation.


2008 ◽  
Vol 72 (5) ◽  
pp. 700-704 ◽  
Author(s):  
Hideyuki Ogawa ◽  
Toshiyuki Ishikawa ◽  
Kouhei Matsushita ◽  
Katsumi Matsumoto ◽  
Tomoaki Ishigami ◽  
...  

2013 ◽  
Vol 168 (3) ◽  
pp. 2867-2868
Author(s):  
Yoshifusa Aizawa ◽  
Nobue Yagihara ◽  
Daisuke Izumki ◽  
Haruo Hanawa ◽  
Makoto Kodama ◽  
...  

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