An Adult With Acute Poststreptococcal Glomerulonephritis Complicated by Hemolytic Uremic Syndrome and Nephrotic Syndrome

2005 ◽  
Vol 46 (4) ◽  
pp. e59-e63 ◽  
Author(s):  
Tomoko Izumi ◽  
Toshitake Hyodo ◽  
Yuichi Kikuchi ◽  
Toshihiko Imakiire ◽  
Tatsuyoshi Ikenoue ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Hemolytic Uremic Syndrome ◽  
Poststreptococcal Glomerulonephritis ◽  
Acute Poststreptococcal Glomerulonephritis ◽  
Uremic Syndrome

scholarly journals C3 and C4 Complements in Glomerular Disorders in Children

2017 ◽  
Vol 18 (3-4) ◽  
pp. 75
Author(s):  
H. Alatas ◽  
I.G.N. Wila Wirya ◽  
T. Tambunan
Keyword(s):  
Nephrotic Syndrome ◽  
Child Health ◽  
Normal Level ◽  
Membranoproliferative Glomerulonephritis ◽  
Kidney Diseases ◽  
Immunosuppressive Treatment ◽  
The Other ◽  
Poststreptococcal Glomerulonephritis ◽  
Acute Poststreptococcal Glomerulonephritis ◽  
Almost All

Seventy children who were hospitalized for kidney diseases in the Nephrological ward Department of Child Health, University of Indonesia, Jakarta were used in this study. Thirty seven patients sufferfng from acute poststreptococcal Glomerulonephritis (A.G.N.), 3 patients with Membranoproliferative Glomerulonephritis (M.P.G.N.) and 30 patients with Nephrotic Syndrome due to other causes were examined for complement concentration. A total of 80 samples were examined for C3 and 25 samples for C4 concentration using the immunediffusion plates. Almost all patients with A.G.N. and M.P.G.N. showed depression of C3. C4 concentration was normal except in 2 patients, 1 with A.G.N. and the other With M.P.G.N. This suggest activation of complement at the C3 level by the alternating pathway in most of the patients. C3 concentration in A.G.N. patients returned to normal after 8-10 weeks. In MPGN the depression was persistent in 2 patients, while in 1 patient it returned to normal level after 3 months of Immunosuppressive treatment.

scholarly journals Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

2020 ◽  
Author(s):  
Diana Carolina Bello-Marquez ◽  
John Fredy Nieto-Rios ◽  
Lina Maria Serna-Higuita ◽  
Alfonso Jose Gonzalez-Vergara
Keyword(s):  
Nephrotic Syndrome ◽  
Hemolytic Uremic Syndrome ◽  
Renal Dysfunction ◽  
Rare Disease ◽  
Alternative Pathway ◽  
Atypical Hemolytic Uremic Syndrome ◽  
Genetic Mutations ◽  
Microangiopathic Hemolytic Anemia ◽  
Uremic Syndrome ◽  
Alternative Pathway Of Complement

Abstract Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement due to genetic mutations. The association with nephrotic syndrome is unusual. We present here a pediatric patient diagnosed with primary atypical hemolytic-uremic syndrome associated with nephrotic syndrome who responded to eculizumab treatment.

scholarly journals Pneumococcal hemolytic uremic syndrome and steroid resistant nephrotic syndrome

2016 ◽  
Vol 9 (4) ◽  
pp. 572-575 ◽  
Author(s):  
Andrew P. Groves ◽  
Patrick Reich ◽  
Binayak Sigdel ◽  
T. Keefe Davis
Keyword(s):  
Nephrotic Syndrome ◽  
Hemolytic Uremic Syndrome ◽  
Steroid Resistant ◽  
Steroid Resistant Nephrotic Syndrome ◽  
Uremic Syndrome

Nephrotic syndrome in a 7-year-old girl with atypical hemolytic uremic syndrome relapse: Answers

2020 ◽  
Author(s):  
Palanisamy Shanmugasundaram Bharathy ◽  
Sriram Krishnamurthy ◽  
Arumugom Archana ◽  
Pediredla Karunakar ◽  
Bobbity Deepthi ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Hemolytic Uremic Syndrome ◽  
Atypical Hemolytic Uremic Syndrome ◽  
Uremic Syndrome

scholarly journals Late Onset Cobalamin Disorder and Hemolytic Uremic Syndrome: A Rare Cause of Nephrotic Syndrome

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Gianluigi Ardissino ◽  
Michela Perrone ◽  
Francesca Tel ◽  
Sara Testa ◽  
Amelia Morrone ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Hemolytic Uremic Syndrome ◽  
Late Onset ◽  
Specific Treatment ◽  
Complete Recovery ◽  
High Dose ◽  
Urine Organic Acid ◽  
Uremic Syndrome ◽  
Diagnostic Work ◽  
Neonates And Infants

Hemolytic uremic syndrome (HUS) is an unrare and severe thrombotic microangiopathy (TMA) caused by several pathogenetic mechanisms among which Shiga toxin-producing Escherichia coli infections and complement dysregulation are the most common. However, very rarely and particularly in neonates and infants, disorders of cobalamin metabolism (CblC) can present with or be complicated by TMA. Herein we describe a case of atypical HUS (aHUS) related to CblC disease which first presented in a previously healthy boy at age of 13.6 years. The clinical picture was initially dominated by nephrotic range proteinuria and severe hypertension followed by renal failure. The specific treatment with high dose of hydroxycobalamin rapidly obtained the remission of TMA and the complete recovery of renal function. We conclude that plasma homocysteine and methionine determinations together with urine organic acid analysis should be included in the diagnostic work-up of any patient with TMA and/or nephrotic syndrome regardless of age.

Nephrotic syndrome in a 7-year-old girl with atypical hemolytic uremic syndrome relapse: Questions

2020 ◽  
Author(s):  
Palanisamy Shanmugasundaram Bharathy ◽  
Sriram Krishnamurthy ◽  
Arumugom Archana ◽  
Pediredla Karunakar ◽  
Bobbity Deepthi ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Hemolytic Uremic Syndrome ◽  
Atypical Hemolytic Uremic Syndrome ◽  
Uremic Syndrome
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