152: A Cost-Effectiveness Model of Phosphate Binders for the Treatment of Hyperphosphatemia in Chronic Kidney Disease (CKD)

2010 ◽  
Vol 55 (4) ◽  
pp. B69
Author(s):  
Michael Keith ◽  
Michael Smyth ◽  
Rashad Carlton ◽  
Brian Meissner
2019 ◽  
Vol 22 ◽  
pp. S913-S914
Author(s):  
M. Lilja ◽  
R. Lauppe ◽  
M. Intorcia ◽  
E.M. Dubois ◽  
P. Csomor ◽  
...  

2019 ◽  
pp. 2-3

Impaired phosphate excretion by the kidney leads to Hyperphosphatemia. It is an independent predictor of cardiovascular disease and mortality in patients with advanced chronic kidney disease (stage 4 and 5) particularly in case of dialysis. Phosphate retention develops early in chronic kidney disease (CKD) due to the reduction in the filtered phosphate load. Overt hyperphosphatemia develops when the estimated glomerular filtration rate (eGFR) falls below 25 to 40 mL/min/1.73 m2. Hyperphosphatemia is typically managed with oral phosphate binders in conjunction with dietary phosphate restriction. These drugs aim to decrease serum phosphate by binding ingested phosphorus in the gastrointestinal tract and its transformation to non-absorbable complexes [1].


Author(s):  
Hamid Ravaghi ◽  
Mahdi Ebrahimnia ◽  
Ali Farzaneh ◽  
Zohreh Rostami ◽  
Mohammad Hasan Hashemi Madani

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