184 Low Serum Bicarbonate Is Associated With Excess Mortality in Kidney Transplant Recipients

2021 ◽  
Vol 77 (4) ◽  
pp. 624-625
Keyword(s):  
Kidney Transplant ◽  
Excess Mortality ◽  
Serum Bicarbonate ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Low Serum

scholarly journals Relationship of Serum Bicarbonate Levels with 1-Year Graft Function in Kidney Transplant Recipients in Switzerland

2019 ◽  
Vol 44 (5) ◽  
pp. 1179-1188 ◽  
Author(s):  
Anna Wiegand ◽  
Nicole Graf ◽  
Marco Bonani ◽  
Diana Frey ◽  
Rudolf P. Wüthrich ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Graft Function ◽  
First Year ◽  
Kidney Graft ◽  
Serum Bicarbonate ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Open Label ◽  
Post Hoc ◽  
Relationship Of

Background: Metabolic acidosis (MA) is common in kidney transplant recipients (KTRs). Several studies have shown that MA is involved in the progression of chronic kidney disease. However, it is unclear if there is also a relationship between serum bicarbonate and graft function after kidney transplantation (KTx). We hypothesized that low serum bicarbonate is associated with a lower estimated glomerular filtration rate (eGFR) 1 year after KTx. Methods: We performed a post hoc analysis of a single-center, open-label randomized trial in 90 KTRs and investigated the relationship of serum bicarbonate and graft function in the first year after KTx. Results: Prevalence of MA was high after KTx (63%) and decreased to 28% after 1 year. Bicarbonate (20.6 ± 3.0 to 22.7 ± 2.7 mmol/L) increased in the first year after transplantation whereas eGFR (53.4 ± 15.8 to 56.9 ± 18.5 mL/min/1.73 m2) did not change significantly. Higher serum bicarbonate (p = 0.029) was associated with higher eGFR in the first year after KTx. Conclusion: Prevalence of MA is high in KTRs. In the first year after KTx, serum bicarbonate was positively correlated with eGFR, suggesting a potential role of MA in kidney graft function.

Association of serum bicarbonate with graft survival and mortality in kidney transplant recipients

2021 ◽  
Author(s):  
Anna Wiegand ◽  
Sandar Felicity Lim ◽  
Seraina von Moos ◽  
Rudolf Peter Wüthrich ◽  
Leonhard Held ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Graft Survival ◽  
Serum Bicarbonate ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

scholarly journals SP726RELATIONSHIP OF SERUM BICARBONATE LEVELS WITH 1-YEAR GRAFT FUNCTION IN KIDNEY TRANSPLANT RECIPIENTS

2018 ◽  
Vol 33 (suppl_1) ◽  
pp. i590-i590
Author(s):  
Anna Wiegand ◽  
Nicole Graf ◽  
Marco Bonani ◽  
Diana Frey ◽  
Rudolf Wüthrich ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Graft Function ◽  
Serum Bicarbonate ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

1631: Evolved Techniques in Hand Assisted Laparoscopic Donor Nephrectomy Improve Outcomes in Kidney Transplant Recipients

2005 ◽  
Vol 173 (4S) ◽  
pp. 441-442
Author(s):  
Peter C. Fisher ◽  
Jeffrey S. Montgomery ◽  
Willam K. Johnston ◽  
J. Stuart Wolf
Keyword(s):  
Kidney Transplant ◽  
Donor Nephrectomy ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Laparoscopic Donor Nephrectomy

Clinical Variables and Outcomes of Kidney Transplant Recipients with Type 2 Diabetes and New-Onset Diabetes after Transplantation in a Predominantly Minority Urban Population

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 541-P
Author(s):  
SANDRA ALEKSIC ◽  
SARA ZAHEDPOUR ANARAKI ◽  
EFFIE TSOMOS ◽  
LAXMI UPADHYAY ◽  
EMILY JAPP ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Kidney Transplant ◽  
Urban Population ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Clinical Variables ◽  
Onset Diabetes ◽  
Predominantly Minority ◽  
New Onset

Long-term follow-up of polyneuropathy in diabetic kidney transplant recipients

Diabetes ◽  
1988 ◽  
Vol 37 (9) ◽  
pp. 1247-1252 ◽  
Author(s):  
J. A. Van der Vliet ◽  
X. Navarro ◽  
W. R. Kennedy ◽  
F. C. Goetz ◽  
J. J. Barbosa ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Diabetic Kidney ◽  
Long Term Follow Up

Factors that Influence the Durability of Transplanted Kidneys in South Africa

2019 ◽  
Vol 21 (2) ◽  
Author(s):  
Hillary Ndemera ◽  
Busisiwe R. Bhengu
Keyword(s):  
South Africa ◽  
Kidney Transplant ◽  
Lifestyle Modification ◽  
P Value ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Kidney Allograft ◽  
Factors Influencing ◽  
Allograft Loss ◽  
Transplanted Kidneys

Kidney transplantation is the cornerstone for renal treatment in patients with end-stage renal failure. Despite improvements in short-term outcomes of renal transplantation, kidney allograft loss remains a huge challenge. The aim of the study was to assess factors influencing the durability of transplanted kidneys among transplant recipients in South Africa. A descriptive cross-sectional study design was used. A random sampling was used to select 171 participants. Data were collected through structured face-to-face interviews developed from in-depth consideration of relevant literature. Data were coded and entered into the SPSS software, version 24. The entered data were analysed using descriptive and inferential statistics. The results revealed that the average durability of transplanted kidneys was 9.07 years among selected kidney transplant recipients in South Africa. Factors associated with the durability of transplanted kidneys included age, the sewerage system and strict immunosuppressive adherence, all with a P-value = .000, followed by the mode of transport (P-value = .001) and support system (P-value = .004). Other variables including demographics, the healthcare system, medication and lifestyle modification engagement were not associated with the durability of transplanted kidneys. Understanding the factors influencing the durability of transplanted kidneys among kidney transplant recipients in South Africa is crucial. The study revealed associated factors and gaps which may be contributory factors to kidney allograft loss. This study provides an opportunity to introduce specific interventions to nephrology professionals to promote prolonged graft durability. It is recommended that a specific intervention model be developed, which targets South African kidney recipients taking into account the significant variables in this study and the socio-economic status of the country.

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