Clostridium septicum Necrotizing Fasciitis of the Forefoot Secondary to Adenocarcinoma of the Colon: Case Report and Review of the Literature

2010 ◽  
Vol 49 (2) ◽  
pp. 159.e1-159.e8 ◽  
Author(s):  
Valerie L. Schade ◽  
Thomas S. Roukis ◽  
Mohamad Haque
2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Abdullateef Abdulkareem ◽  
Ryan S. D’Souza ◽  
Oluwaseun Shogbesan ◽  
Anthony Donato

Necrotizing fasciitis is a fulminant soft tissue infection characterized by rapid progression and high mortality. Rituximab is a generally well-tolerated immunosuppresive medication used for B-cell malignancies and some rheumatological disorders. We report a case of a 69-year-old male with chronic lymphocytic leukemia who suffered necrotizing fasciitis of his left lower extremity secondary to Clostridium septicum 7 weeks after treatment with rituximab. Despite immediate intravenous antimicrobial therapy and emergent fasciotomy with extensive debridement, his hospital course was complicated by septic shock and he required an above-the-knee amputation. Physicians need to be aware of the possibility of necrotizing fasciitis in patients presenting with skin infections after rituximab therapy.


2004 ◽  
Vol 19 (3) ◽  
pp. 264-267 ◽  
Author(s):  
Chris Braumann ◽  
Michael Schwabe ◽  
Juergen Ordemann ◽  
Christoph A. Jacobi

2001 ◽  
Vol 42 (4) ◽  
pp. 272-277 ◽  
Author(s):  
G.R. Ballon-Landa ◽  
G. Gherardi ◽  
B. Beall ◽  
S. Krosner ◽  
V. Nizet

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
John Rausch ◽  
Marc Foca

We report a case of necrotizing fasciitis with an accompanying toxic shock syndrome caused by Group G Streptococcus in a pediatric patient with a lymphatic malformation. Pediatricians need to be aware of the possibility of such infections, especially in those with vascular/lymphatic malformations, as early treatment is critical for survival.


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