Correction: Development and validation of the SIMPLE endoscopic classification of diminutive and small colorectal polyps

Endoscopy ◽  
2018 ◽  
Vol 50 (08) ◽  
pp. C8-C8 ◽  
Author(s):  
Marietta Iacucci ◽  
Cristina Trovato ◽  
Marco Daperno ◽  
Oluseyi Akinola ◽  
David Greenwald ◽  
...  
2021 ◽  
Vol 160 (6) ◽  
pp. S-376
Author(s):  
Eladio Rodriguez-Diaz ◽  
Gyorgy Baffy Wai-Kit Lo ◽  
Hiroshi Mashimo ◽  
Aparna Repaka ◽  
Alexander Goldowsky ◽  
...  

2014 ◽  
Vol 146 (5) ◽  
pp. S-602-S-603
Author(s):  
Antonio Tursi ◽  
Giovanni Brandimarte ◽  
Francesco Di Mario ◽  
Walter Elisei ◽  
Luigi Di Cesare ◽  
...  

2014 ◽  
Vol 46 ◽  
pp. S14-S15
Author(s):  
A. Tursi ◽  
G. Brandimarte ◽  
F. Di Mario ◽  
A. Andreoli ◽  
M.L. Annunziata ◽  
...  

2014 ◽  
Vol 33 (1) ◽  
pp. 68-76 ◽  
Author(s):  
Antonio Tursi ◽  
Giovanni Brandimarte ◽  
Francesco Di Mario ◽  
Arnaldo Andreoli ◽  
Maria Laura Annunziata ◽  
...  

Background: A validated endoscopic classification of diverticular disease (DD) of the colon is lacking at present. Our aim was to develop a simple endoscopic score of DD: the Diverticular Inflammation and Complication Assessment (DICA) score. Methods: The DICA score for DD resulted in the sum of the scores for the extension of diverticulosis, the number of diverticula per region, the presence and type of inflammation, and the presence and type of complications: DICA 1 (≤3), DICA 2 (4-7) and DICA 3 (>7). A comparison with abdominal pain and inflammatory marker expression was also performed. A total of 50 videos of DD patients were reassessed in order to investigate the predictive role of DICA on the outcome of the disease. Results: Overall agreement in using DICA was 0.847 (95% confidence interval, CI, 0.812-0.893): 0.878 (95% CI 0.832-0.895) for DICA 1, 0.765 (95% CI 0.735-0.786) for DICA 2 and 0.891 (95% CI 0.845-0.7923) for DICA 3. Intra-observer agreement (kappa) was 0.91 (95% CI 0.886-0.947). A significant correlation was found between the DICA score and C-reactive protein values (p = 0.0001), as well as between the median pain score and the DICA score (p = 0.0001). With respect to the 50 patients retrospectively reassessed, occurrence/recurrence of disease complications was recorded in 29 patients (58%): 10 (34.5%) were classified as DICA 1 and 19 (65.5%) as DICA 2 (p = 0.036). Conclusions: The DICA score is a simple, reproducible, validated and easy-to-use endoscopic scoring system for DD of the colon.


1999 ◽  
Vol 123 (5) ◽  
pp. 404-410
Author(s):  
Hidejiro Yokoo ◽  
M. Irtaza Usman ◽  
Susan Wheaton ◽  
Patricia A. Kampmeier

Abstract Background.—The histologic classification of colorectal polyps is well established. However, practicing pathologists may still occasionally encounter colorectal polyps that are difficult to classify. We studied 6 colorectal polyps that showed uncommon histologic features that have not been described in the English language literature. Materials and Methods.—The polyps were studied using standard hematoxylin-eosin stain, mucin histochemistry, and electron microscopy. Results.—The 6 polyps we studied showed extensive papillary and villous structures with alternating villi and crypts. The villi were lined by well-differentiated absorptive cells, whereas the crypts were lined by immature glandular cells, thus mimicking the histology of the small intestinal mucosa. Conclusions.—These polyps appear to represent a variant of the hyperplastic polyp, in as much as cellular maturation (immature glandular cells differentiate into the mature surface absorptive cells) is the essential feature distinguishing hyperplastic polyps from adenomas.


2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
A. J. McCarthy ◽  
S. M. O’Reilly ◽  
J. Shanley ◽  
R. Geraghty ◽  
E. J. Ryan ◽  
...  

Background. As the malignant potential of sessile serrated lesions/polyps (SSL/Ps) and traditional serrated adenomas (TSAs) has been clearly demonstrated, it is important that serrated polyps are identified and correctly classified histologically. Aim. Our aim was to characterize the clinicopathological features of a series of SSL/Ps & TSAs, to assess the accuracy of the pathological diagnosis, the incidence, and the rate of dysplasia in SSL/Ps & TSAs. Methods. We identified all colorectal serrated polyps between 01/01/2004 and 31/05/2016, by searching the laboratory information system for all cases assigned a “serrated adenoma” SNOMED code. All available and suitable slides were reviewed by one pathologist, who was blinded to the original diagnosis and the site of the polyp. Subsequently discordant cases, SSL/Ps with dysplasia, and all TSAs were reviewed by a second pathologist. Results. Over a 149-month period, 759 “serrated adenoma” polyps were identified, with 664 (from 523 patients) available for review. 41.1% were reviewed by both pathologists; 15.1% (100/664) were reclassified, with the majority being changed from SSL/P to hyperplastic polyp (HYP) (66/664; 9.9%). 80.3% of these HYPs were located in the left colon, and the majority exhibited prolapse effect. There were 520 SSL/Ps (92.2%) & 40 TSAs (7.1%). The majority of SSL/Ps were in the right colon (86.7%) and were small (64.5% <1 cm), while most TSAs were in the left colon (85.7%) and were large (73.1%≥1 cm). 6.7% of SSL/Ps exhibited dysplasia, the majority of which were large (66.7%≥1 cm). Following consensus review, 13/520 (2.5%) SSL/Ps were downgraded from SSL/P with dysplasia to SSL/P without dysplasia. Detection of SSL/Ps peaked in the most recent years reviewed (87.5% reported between 2013 and 2016, inclusive), coinciding with the introduction of “BowelScreen” (the Irish FIT-based colorectal cancer screening programme). Conclusions. Awareness of, and adherence to, diagnostic criteria is essential for accurate classification of colorectal polyps.


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