Endoscopic ultrasound-guided therapy of gastric varices with coils plus cyanoacrylate injection versus coiling alone: getting evidence-based data but are they comparable?

Abstract Introduction Conventional n-butyl-cyanoacrylate (CYA) recommended for secondary prophylaxis of gastric varices (GV) is associated with significant rebleeding and glue embolism. Limited data are available on more successful and less risky endoscopic ultrasound-guided coils and CYA (EUS-Coils-CYA) injection in GV. Methods We present a retrospective case series of 12 patients with GV bleeding managed successfully with EUS-Coils-CYA injection leading to variceal eradication in 11 patients. Results From January 2018 to June 2019, 12 cases of GV, which were either bleeding or bled recently, were included. Complete obliteration was achieved in 91.6% of patients with 100% technical success. Mean number of deployed coils and volume of injected CYA glue were 1.16 and 1.58 mL, respectively. Conclusions EUS-guided angiotherapy is an effective and safe intervention for managing GV bleeding with high technical success rate.

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Endoscopic‐ultrasound‐guided coil and cyanoacrylate embolization for gastric varices and the roles of endoscopic Doppler and endosonographic varicealography in vascular targeting

Digestive Endoscopy ◽

10.1111/den.13305 ◽

2018 ◽

Vol 31 (3) ◽

pp. 283-290 ◽

Cited By ~ 7

Author(s):

Carlos Robles‐Medranda ◽

Manuel Valero ◽

Joao Autran Nebel ◽

Sylon Ribeiro Britto Junior ◽

Miguel Puga‐Tejada ◽

...

Keyword(s):

Endoscopic Ultrasound ◽

Gastric Varices ◽

Vascular Targeting ◽

Ultrasound Guided

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1036 COILS + CYANOACRYLATE VS. COILS ALONE IN THE ENDOSCOPIC ULTRASOUND-GUIDED MANAGEMENT OF GASTRIC VARICES [GOV II AND IGV I]: A RANDOMIZED, CONTROLLED THERAPEUTIC TRIAL.

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2018.04.1369 ◽

2018 ◽

Vol 87 (6) ◽

pp. AB145 ◽

Cited By ~ 1

Author(s):

Carlos Robles-Medranda ◽

Manuel Valero ◽

Miguel Soria ALcívar ◽

Miguel Puga-Tejada ◽

Roberto Oleas ◽

...

Keyword(s):

Endoscopic Ultrasound ◽

Gastric Varices ◽

Therapeutic Trial ◽

Ultrasound Guided ◽

Randomized Controlled

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Endoscopic Ultrasound-Guided Therapies in Pancreatic Neoplasms

BioMed Research International ◽

10.1155/2015/731049 ◽

2015 ◽

Vol 2015 ◽

pp. 1-12

Author(s):

Dennis Yang ◽

Christopher J. DiMaio

Keyword(s):

Pancreatic Cancer ◽

Targeted Therapy ◽

Endoscopic Ultrasound ◽

Pancreatic Neoplasms ◽

Ultrasound Guided ◽

Poor Survival ◽

Minimally Invasive Approach ◽

Diagnostic Modality ◽

Invasive Approach ◽

Guided Therapy

Endoscopic ultrasound (EUS) has evolved from being primarily a diagnostic modality into an interventional endoscopic tool for the management of both benign and malignant gastrointestinal illnesses. EUS-guided therapy has garnered particular interest as a minimally invasive approach for the treatment of pancreatic cancer, a disease often complicated by its aggressive course and poor survival. The potential advantage of an EUS-guided approach revolves around real-time imaging for targeted therapy of a difficult to reach organ. In this review, we focus on EUS-guided therapies for pancreatic neoplasms.

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