The Use of Ultrasound to Detect Small-for-Gestational-Age Infants in Patients with Elevated Human Chorionic Gonadotropin on Maternal Serum Screening

2009 ◽  
Vol 27 (02) ◽  
pp. 173-180 ◽  
Author(s):  
Tamera Hatfield ◽  
Aaron Caughey ◽  
David Lagrew ◽  
Ryan Heintz ◽  
Judith Chung
Keyword(s):  
Chorionic Gonadotropin ◽  
Gestational Age ◽  
Human Chorionic Gonadotropin ◽  
Small For Gestational Age ◽  
Maternal Serum ◽  
Maternal Serum Screening ◽  
Serum Screening

Prediction of Smallness for Gestational Age by Maternal Serum Human Chorionic Gonadotropin Levels and by Uterine Artery Doppler Study

2000 ◽  
Vol 16 (1) ◽  
pp. 42-46 ◽  
Author(s):  
Kei Miyakoshi ◽  
Mamoru Tanaka ◽  
Danilo Gabionza ◽  
Hitoshi Ishimoto ◽  
Toyohiko Miyazaki ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Gestational Age ◽  
Human Chorionic Gonadotropin ◽  
Uterine Artery ◽  
Maternal Serum ◽  
Uterine Artery Doppler ◽  
Doppler Study

Free β-Chorionic Gonadotropin: A Cross-Reactivity Study of Two Immunometric Assays Used in Prenatal Maternal Serum Screening for Down's Syndrome

1993 ◽  
Vol 30 (1) ◽  
pp. 94-98 ◽  
Author(s):  
James N Macri ◽  
Kevin Spencer ◽  
Robert W Anderson ◽  
Edward J Cook
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Detection Efficiency ◽  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Cross Reactivity ◽  
Maternal Serum ◽  
Glycoprotein Hormones ◽  
Maternal Serum Screening ◽  
Reactivity Study

We have evaluated the cross-reactivity characteristics of two distinct immunometric assays for the measurement of free β-human chorionic gonadotropin (free β). These maternal serum assays have been used in the initial studies which evaluated free β as a marker in the prenatal detection of Down's syndrome. It has been suggested that free β assays are subject to substantial potential for cross-reactivity. To confirm that free β was the analyte responsible for enhanced detection efficiency both non-competitive and competitive cross-reactivity evaluations were undertaken. These studies demonstrated acceptably small cross-reactivity to other glycoprotein hormones or their β components. We conclude that properly designed free β assays will provide specific analyte measurement and improved detection efficiency in Down's syndrome screening.

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