Dean Watson vom 7. – 9. April 2011 in Yverdon: The Role of C0 – C3 Segmental Dysfunction in Primary Headache

2011 ◽  
Vol 15 (03) ◽  
pp. 135-136
Author(s):  
C. Engel
Keyword(s):  
Primary Headache ◽  
Segmental Dysfunction

Brain structure and function related to headache: Brainstem structure and function in headache

Cephalalgia ◽  
2018 ◽  
Vol 39 (13) ◽  
pp. 1635-1660 ◽  
Author(s):  
Marta Vila-Pueyo ◽  
Jan Hoffmann ◽  
Marcela Romero-Reyes ◽  
Simon Akerman
Keyword(s):  
Primary Headache ◽  
Structure And Function ◽  
Affective Processing ◽  
Primary Headaches ◽  
Headache Disorders ◽  
Primary Headache Disorders ◽  
Brain Structure And Function ◽  
And Function ◽  
The Brain

Objective To review and discuss the literature relevant to the role of brainstem structure and function in headache. Background Primary headache disorders, such as migraine and cluster headache, are considered disorders of the brain. As well as head-related pain, these headache disorders are also associated with other neurological symptoms, such as those related to sensory, homeostatic, autonomic, cognitive and affective processing that can all occur before, during or even after headache has ceased. Many imaging studies demonstrate activation in brainstem areas that appear specifically associated with headache disorders, especially migraine, which may be related to the mechanisms of many of these symptoms. This is further supported by preclinical studies, which demonstrate that modulation of specific brainstem nuclei alters sensory processing relevant to these symptoms, including headache, cranial autonomic responses and homeostatic mechanisms. Review focus This review will specifically focus on the role of brainstem structures relevant to primary headaches, including medullary, pontine, and midbrain, and describe their functional role and how they relate to mechanisms of primary headaches, especially migraine.

The role of stressful life events in the onset of chronic primary headache

Pain ◽  
1990 ◽  
Vol 40 (1) ◽  
pp. 65-75 ◽  
Author(s):  
Giuseppe De Benedittis ◽  
Ariberto Lorenzetti ◽  
Antonio Fieri
Keyword(s):  
Life Events ◽  
Stressful Life Events ◽  
Primary Headache ◽  
Stressful Life

MMPI Personality Profiles in Patients With Primary Headache Syndromes

Cephalalgia ◽  
1991 ◽  
Vol 11 (6) ◽  
pp. 263-268 ◽  
Author(s):  
Volker Pfaffenrath ◽  
Josef Hummelsberger ◽  
Walter Pöllmann ◽  
Holger Kaube ◽  
Michael Rath
Keyword(s):  
Cluster Headache ◽  
Minnesota Multiphasic Personality Inventory ◽  
Normal Population ◽  
Primary Headache ◽  
Tension Type Headache ◽  
Personality Profiles ◽  
Mean Values ◽  
Ihs Criteria ◽  
Type Headache

The role of psychological factors in the course of primary headache syndromes is still controversial. Using the Minnesota Multiphasic Personality Inventory (MMPI) we investigated the personality profiles of 434 headache patients (160 migraineurs, 95 with tension type headache, 30 with cluster headache and 149 with combination headache) in accordance with the IHS criteria. In the first three MMPI scales (hypochondria, depression, hysteria) there was a slight increase in T mean values to over 60, but still in the range of two standard deviations of the normal population. There were no statistically significant differences between the four headache groups and between patients with and without analgesic abuse. It was impossible to distinguish headache groups on the basis of their personality profiles by means of reclassification with discriminant analysis. In a cluster analysis, patients with cluster headache showed the highest number (20%) of abnormalities, but also the highest percentage (13%) of completely normal results. Our findings- a cross section analysis of personality profiles-contradict many other MMPI-based studies.

Were we wrong about the role of psychiatric comorbidities in primary headache?

Pain ◽  
2009 ◽  
Vol 146 (1) ◽  
pp. 11-12 ◽  
Author(s):  
Todd A. Smitherman ◽  
Donald B. Penzien
Keyword(s):  
Primary Headache ◽  
Psychiatric Comorbidities

Platelet Models and Their Possible Usefulness in the Study of Migraine Pathogenesis

Cephalalgia ◽  
1995 ◽  
Vol 15 (4) ◽  
pp. 265-271 ◽  
Author(s):  
G D'Andrea ◽  
AR Cananzi ◽  
F Perini ◽  
L Hasselmark
Keyword(s):  
Primary Headache ◽  
The Other ◽  
Clinical Aspects ◽  
Metabolic Characteristics ◽  
Dense Bodies ◽  
Migraine Pathogenesis ◽  
Serotonin Turnover ◽  
The One

Platelets may be linked to migraine. On the one hand they are activated during the migraine attack and thus may participate in the pathogenesis of the disorder (the nature of this activation is still unknown). In order to understand this platelet anomaly, we discuss the data available in the literature. In particular, we review recent in vitro studies of a-granules and dense bodies secretion, and aggregation induced by collagen and PAF. On the other hand, platelets share many metabolic characteristics with serotonergic neurons and endothelial cells. Accordingly, platelets have been used to investigate the possible role of serotonin turnover and nitric oxide function in migraine. In both cases, the data obtained have shown peculiar abnormalities that may explain pathogenetic and clinical aspects of primary headache.

INDOMETHACIN TEST USAGE AT UNITED KINGDOM TERTIARY CENTRES OVER 20 YEARS-AN AUDIT

2015 ◽  
Vol 86 (11) ◽  
pp. e4.127-e4
Author(s):  
Pyari Bose ◽  
DG Palethorpe ◽  
J Marin ◽  
A Nesbitt ◽  
J Lowe ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Test Procedure ◽  
Primary Headache ◽  
Hemicrania Continua ◽  
Paroxysmal Hemicrania ◽  
Serious Adverse Events ◽  
Data Set ◽  
Primary Headache Disorders ◽  
Test Usage

BackgroundIndomethacin-responsive trigeminal autonomic cephalalagias (TACS), paroxysmal hemicrania (PH) and hemicrania continua (HC), are unique, important syndromes to understand.AimEvaluation of the role of the placebo-controlled indomethacin test (P-Indotest) in the diagnosis of primary headache disorders.MethodPatients notes, clinic letters and headache diaries of patients under our care (PJG) over a 20 year period across various UK Neurology tertiary care centres were examined to obtain data against an audit collection tool. A pre-determined set of data were extracted, and the test procedure reviewed for compliance against a standard with minimum data set requirement by an unblinded observer. The original test score was noted, and prospectively re-scored by a blinded observer.ResultsPatients (n=7; 4 female) were aged from 24 to 51 years. The majority (85%) had side locked headache. P-Indotest was positive in 78% of the cases with patients having either HC or PH. Of all patients tested, 42% had unilateral photophobia and phonophobia and all these cases had a positive response. No serious adverse events were noted. Sleepiness was often reported on the active treatment as was transient worsening of headache in unilateral chronic migraine. Further data is being compiled.ConclusionThe P-IndoTest is a reliable and safe test and should in the diagnosis of patients with possible indomethacin sensitive TACs. While far from ideal, a positive indomethacin test does identify a particular biology and should be retained as a diagnostic marker of PH and HC until its basis is understood.

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