Comparison of the Effects of Two-Staged Nerve Graft Application and One-Stage Nerve Graft Application on Axonal Regeneration in Long Nerve Defect Reconstruction

The percentage of axons from different types of neurons regenerating through the site of repair was assessed by retrograde horseradish peroxidase labelling in 30 male SD rats. These rats were randomly divided into groups and underwent epineurial, perineurial suturing and 4 mm nerve graft for transected peroneal nerves in lower limbs on one side. The contralateral nerves were not injured and served as controls. The number of labelled neurons in the experimental side divided by those in the control gave a percentage of regeneration. Four to 9 weeks after nerve repair, axonal regeneration through the repair site was assessed by number, location and diameter. Results revealed that the percentage of motor axons crossing the nerve repair site was the same as the sensory axons. The percentage of neurons with axons innervating muscle spindles was statistically lower that those innervating the other end organs. Perineurial repair produced a higher percentage of motor axons across the repair than epineurial repair or nerve graft.

Download Full-text

Implantation of Neurotrophic Factor-Treated Sensory Nerve Graft Enhances Survival and Axonal Regeneration of Motoneurons After Spinal Root Avulsion

Journal of Neuropathology & Experimental Neurology ◽

10.1097/nen.0b013e31819344a9 ◽

2009 ◽

Vol 68 (1) ◽

pp. 94-101 ◽

Cited By ~ 18

Author(s):

Tak-Ho Chu ◽

Suk-Yee Li ◽

Anchen Guo ◽

Wai-Man Wong ◽

Qiuju Yuan ◽

...

Keyword(s):

Neurotrophic Factor ◽

Axonal Regeneration ◽

Sensory Nerve ◽

Nerve Graft ◽

Root Avulsion ◽

Spinal Root

Download Full-text

Peripheral Nerve Graft-Mediated Axonal Regeneration

Neural Regeneration ◽

10.1016/b978-0-12-801732-6.00019-7 ◽

2015 ◽

pp. 291-299 ◽

Cited By ~ 2

Author(s):

Veronica J. Tom ◽

John D. Houle

Keyword(s):

Peripheral Nerve ◽

Axonal Regeneration ◽

Nerve Graft ◽

Peripheral Nerve Graft

Download Full-text

One-Stage Complex Achilles Tendon Defect Reconstruction with an Achilles Tendon Allograft and a Gracilis Free Flap

Foot & Ankle International ◽

10.3113/fai.2010.0634 ◽

2010 ◽

Vol 31 (7) ◽

pp. 634-638 ◽

Cited By ~ 9

Author(s):

Efstathios G. Lykoudis ◽

George V. Contodimos ◽

Stavros Ristanis ◽

Anastasios D. Georgoulis ◽

Spyros A. Lazarou

Keyword(s):

Achilles Tendon ◽

Free Flap ◽

Defect Reconstruction ◽

One Stage ◽

Tendon Defect ◽

Tendon Allograft ◽

Achilles Tendon Allograft

Download Full-text

Mastoid Skin Island Flap: A Simple Technique for Conchal Defect Reconstruction

Canadian Journal of Plastic Surgery ◽

10.1177/229255039300100303 ◽

1993 ◽

Vol 1 (3) ◽

pp. 137-140

Author(s):

O Antonyshyn

Keyword(s):

Skin Graft ◽

External Auditory Canal ◽

Simple Technique ◽

Island Flap ◽

Defect Reconstruction ◽

One Stage ◽

Skin Island ◽

One Stage Reconstruction ◽

Graft Reconstruction ◽

Skin Island Flap

O Antonyshyn. Mastoid skin island flap: A simple technique for conchal defect reconstruction. Can J Plast Surg 1993; 1(3): 137-140. Conchal defects resulting from tumour excision can pose a difficult reconstructive problem. These defects generally involve the entire concha and occasionally extend to the external auditory canal. Under these circumstances, skin graft reconstruction is unsuitable. A simple technique of conchal reconstruction using a mastoid skin island flap is described. The flap provides a reliable one-stage reconstruction of the concha and posterior conchal wall.

Download Full-text