The Role of Microglia in Prevention of Hemorrhagic Transformation and Blood Flow Regulation after Ischemic Stroke

2014 ◽  
Vol 75 (S 02) ◽  
Author(s):  
M. Hugelshofer ◽  
A. Keller ◽  
M. Wurnig ◽  
L. Regli ◽  
A. Aguzzi
Keyword(s):  
Blood Flow ◽  
Ischemic Stroke ◽  
Flow Regulation ◽  
Hemorrhagic Transformation ◽  
Blood Flow Regulation

Role of Endothelin-1 in Choroidal Blood Flow Regulation during Isometric Exercise in Healthy Humans

2003 ◽  
Vol 44 (2) ◽  
pp. 728 ◽  
Author(s):  
Gabriele Fuchsja¨ger-Mayrl ◽  
Alexandra Luksch ◽  
Magdalena Malec ◽  
Elzbieta Polska ◽  
Michael Wolzt ◽  
...  
Keyword(s):  
Blood Flow ◽  
Isometric Exercise ◽  
Flow Regulation ◽  
Choroidal Blood Flow ◽  
Endothelin 1 ◽  
Healthy Humans ◽  
Blood Flow Regulation

scholarly journals Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation

PLoS ONE ◽  
2013 ◽  
Vol 8 (1) ◽  
pp. e53390 ◽  
Author(s):  
András Iring ◽  
Éva Ruisanchez ◽  
Miriam Leszl-Ishiguro ◽  
Béla Horváth ◽  
Rita Benkő ◽  
...  
Keyword(s):  
Blood Flow ◽  
Flow Regulation ◽  
Blood Flow Regulation

Role of NO in Choroidal Blood Flow Regulation during Isometric Exercise in Healthy Humans

2003 ◽  
Vol 44 (2) ◽  
pp. 734 ◽  
Author(s):  
Alexandra Luksch ◽  
Elzbieta Polska ◽  
Andrea Imhof ◽  
Joanne Schering ◽  
Gabriele Fuchsja¨ger-Mayrl ◽  
...  
Keyword(s):  
Blood Flow ◽  
Isometric Exercise ◽  
Flow Regulation ◽  
Choroidal Blood Flow ◽  
Healthy Humans ◽  
Blood Flow Regulation

Role of Nitric Oxide in Choroidal Blood Flow Regulation during Light/Dark Transitions

2007 ◽  
Vol 48 (9) ◽  
pp. 4215 ◽  
Author(s):  
Karl-Heinz Huemer ◽  
Gerhard Garhofer ◽  
Tina Aggermann ◽  
Julia Kolodjaschna ◽  
Leopold Schmetterer ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Flow Regulation ◽  
Choroidal Blood Flow ◽  
Blood Flow Regulation

scholarly journals Radiological predictors of hemorrhagic transformation after acute ischemic stroke: An evidence-based analysis

2020 ◽  
Vol 33 (2) ◽  
pp. 118-133 ◽  
Author(s):  
Nada Elsaid ◽  
Wessam Mustafa ◽  
Ahmed Saied
Keyword(s):  
Blood Flow ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Ct Perfusion ◽  
Treatment Plan ◽  
Hemorrhagic Transformation ◽  
Lesion Volume ◽  
Ischemic Lesion ◽  
Blood Brain Barrier Disruption

Hemorrhagic transformation (HT) is one of the most common adverse events related to acute ischemic stroke (AIS) that affects the treatment plan and clinical outcome. Identification of a sensitive radiological marker may influence the controversial thrombolytic decision in the setting of AIS and may at a minimum indicate more intensive monitoring or further prophylactic interventions. In this article we summarize possible radiological biomarkers and the role of different radiological modalities including computed tomography (CT), magnetic resonance imaging, angiography, and ultrasound in predicting HT. Different radiological indices of early ischemic changes, large ischemic lesion volume, severe blood flow restriction, blood-brain barrier disruption, poor collaterals and high blood flow velocities have been reported to be associated with higher risk of HT. The current levels of evidence of the available studies highlight the role of the different CT perfusion parameters in predicting HT. Further large standardized studies are recommended to compare the sensitivity and specificity of the different radiological markers combined and delineate the most reliable predictor.

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