Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer-Supported Formate and Magnesium
Keyword(s):
Low Cost
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Aromatic nitro compounds were chemoselectively reduced to the corresponding amines using recyclable polymer-supported formate as a hydrogen donor in the presence of low-cost magnesium powder at room temperature. Use of the immobilized hydrogen donor affords the product amine in excellent yield (90–97%) without the need for any chromatographic purification steps. This method was found to be highly facile with selectivity over several other functional groups, such as halogen, alkene, nitrile, carbonyl, ester, amide, methoxy, phenol, and hydroxyl groups.
2018 ◽
Vol 7
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pp. 317-327
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2000 ◽
Vol 41
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pp. 5603-5606
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2011 ◽
Vol 35
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pp. 112-115
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2014 ◽
Vol 1033-1034
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pp. 18-21
2009 ◽
Vol 10
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pp. 1207-1211
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