scholarly journals Methanal Extrusion in ipso-Substitution Reactions of Hydroxymethylindoles

2017 ◽  
Vol 70 (11) ◽  
pp. 1188 ◽  
Author(s):  
Jeremy C. Dobrowolski ◽  
Kittiya Somphol ◽  
Mardi Santoso ◽  
Hung Duong ◽  
Christopher R. Gardner ◽  
...  
Keyword(s):  
Electrophilic Substitution ◽  
Macrocyclic Compounds ◽  
Substitution Reactions ◽  
Ipso Substitution ◽  
Acid Catalysed Reactions

A range of 3-hydroxymethylindoles undergo acid-catalysed reactions involving ipso-electrophilic substitution with the extrusion of methanal and the formation of diindolylmethane moieties. Both inter- and intramolecular processes lead to macrocyclic compounds 10 and 14.

The Chemistry of Triazine Isomers: Structures, Reactions, Synthesis and Applications

2020 ◽  
Vol 20 ◽  
Author(s):  
Neelottama Kushwaha ◽  
C S Sharma
Keyword(s):  
Basic Property ◽  
Electrophilic Substitution ◽  
Antimicrobial Agents ◽  
Resonance Energy ◽  
Heterocyclic Ring ◽  
Ring System ◽  
Agricultural Fields ◽  
Substitution Reactions ◽  
Anti Cancer ◽  
Benzene Structure

: Triazine is the six-membered heterocyclic ring containing three nitrogen which replaces carbon-hydrogen unit in the benzene ring. Based on nitrogen position present in the ring system, it is categorized in three isomeric forms i.e.1, 2, 3-triazine (vicinal triazine), 1, 2, 4-triazine (asymmetrical triazine or isotriazine) and 1, 3, 5-triazine (symmetrical or s-triazine or cyanidine). Triazines have weakly basic property. Its isomers have much weaker resonance energy than benzene structure, so nucleophilic substitution reactions are more preferred than electrophilic substitution reactions. Triazine isomers and their derivatives are known to play important roles possessing various activities in medicinal and agricultural fields such as anti-cancer, antiviral, fungicidal, insecticidal, bactericidal, herbicidal, antimalarial and antimicrobial agents.

ChemInform Abstract: RADICAL ALKYLDENITRATION. A SYNTHETICALLY USEFUL EXAMPLE OF HOMOLYTIC AROMATIC IPSO-SUBSTITUTION REACTIONS

1978 ◽  
Vol 9 (24) ◽  
Author(s):  
L. TESTAFERRI ◽  
M. TIECCO ◽  
M. TINGOLI ◽  
M. FIORENTINO ◽  
L. TROISI
Keyword(s):  
Substitution Reactions ◽  
Ipso Substitution

Organotellurium compounds: an overview of synthetic methodologies

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Muhammad Irfan ◽  
Rabia Rehman ◽  
Mohd. R. Razali ◽  
Muhammad Adnan Iqbal ◽  
◽  
...  
Keyword(s):  
Material Science ◽  
Electrophilic Substitution ◽  
Comprehensive Understanding ◽  
Substitution Reactions ◽  
Current Review ◽  
Synthetic Routes ◽  
Electrophilic Substitution Reactions ◽  
Synthetic Methodologies ◽  
Organotellurium Compounds

AbstractIn wake of emerging applications of organotellurium compounds in biological and material science avenues, the current review describes their key synthetic methodologies while focusing the synthesis of organotellurium compounds through five ligand-to-metal linkages including carbon; carbon-oxygen; carbon-nitrogen; carbon-metal; carbon-sulfur to tellurium. In all of these linkages whether tellurium links with ligands through a complicated or simple pathways, it is often governed through electrophilic substitution reactions. The present study encompasses these major synthetic routes so as to acquire comprehensive understanding of synthetic organotellurium compounds.

Electrophilic substitution reactions of acylated 2-aminoindole derivatives

1985 ◽  
Vol 21 (7) ◽  
pp. 782-785 ◽  
Author(s):  
E. S. Besidskii ◽  
G. A. Golubeva ◽  
L. A. Sviridova
Keyword(s):  
Electrophilic Substitution ◽  
Substitution Reactions ◽  
Electrophilic Substitution Reactions

ANOMALOUS ELECTROPHILIC SUBSTITUTION REACTIONS IN 3,3'-LINKED DIPYRROMETHANES

1996 ◽  
Vol 2 (1) ◽  
Author(s):  
Sam H. Leung ◽  
Liem T. Nguyen ◽  
Kevin M. Smith
Keyword(s):  
Electrophilic Substitution ◽  
Substitution Reactions ◽  
Electrophilic Substitution Reactions

ChemInform Abstract: Bisindoles. Part 27. Electrophilic Substitution Reactions in the 7,7′-Dichlorobis-(5-indolyl)methane Series.

ChemInform ◽  
1990 ◽  
Vol 21 (21) ◽  
Author(s):  
DZH. ZEGKHUGKH ◽  
SH. A. SAMSONIYA ◽  
D. O. KADZHRISHVILI ◽  
L. M. MAMALADZE
Keyword(s):  
Electrophilic Substitution ◽  
Substitution Reactions ◽  
Electrophilic Substitution Reactions
Sign in / Sign up

Export Citation Format

Share Document