Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0400380101 ◽

2004 ◽

Vol 101 (11) ◽

pp. 3921-3926 ◽

Author(s):

P. Reddy ◽

Y. Maeda ◽

K. Hotary ◽

C. Liu ◽

L. L. Reznikov ◽

...

Keyword(s):

Histone Deacetylase ◽

Graft Versus Host Disease ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Suberoylanilide Hydroxamic Acid ◽

Graft Versus Host ◽

Graft Versus Leukemia ◽

Deacetylase Inhibitor ◽

Acute Graft ◽

Graft Versus Leukemia Effect

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Faculty Opinions recommendation of Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1005948.208465 ◽

2004 ◽

Author(s):

Bruce Blazar

Keyword(s):

Histone Deacetylase ◽

Graft Versus Host Disease ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Suberoylanilide Hydroxamic Acid ◽

Graft Versus Host ◽

Graft Versus Leukemia ◽

Deacetylase Inhibitor ◽

Acute Graft ◽

Graft Versus Leukemia Effect

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Suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect by inhibiting histone deacetylation

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2003.12.061 ◽

2004 ◽

Vol 10 ◽

pp. 17

Author(s):

P. Reddy ◽

Y. Maeda ◽

K. Hotary ◽

C.A. Dinarello ◽

J.L. Ferrara

Keyword(s):

Graft Versus Host Disease ◽

Hydroxamic Acid ◽

Histone Deacetylation ◽

Suberoylanilide Hydroxamic Acid ◽

Host Disease ◽

Graft Versus Host ◽

Graft Versus Leukemia ◽

Acute Graft ◽

Graft Versus Leukemia Effect

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Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1

Experimental Hematology ◽

10.1016/j.exphem.2006.02.014 ◽

2006 ◽

Vol 34 (6) ◽

pp. 776-787 ◽

Author(s):

Corinna Leng ◽

Margarethe Gries ◽

Judy Ziegler ◽

Anna Lokshin ◽

Paolo Mascagni ◽

...

Keyword(s):

Histone Deacetylase ◽

Graft Versus Host Disease ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Inflammatory Cytokine ◽

Host Disease ◽

Graft Versus Host ◽

Deacetylase Inhibitor ◽

Cytokine Milieu

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Phase I trial of histone deacetylase inhibitor panobinostat in addition to glucocorticoids for primary therapy of acute graft-versus-host disease

Bone Marrow Transplantation ◽

10.1038/s41409-018-0163-z ◽

2018 ◽

Vol 53 (11) ◽

pp. 1434-1444 ◽

Author(s):

Lia Perez ◽

Hugo Fernandez ◽

Pedro Horna ◽

Marcie Riches ◽

Frederick Locke ◽

...

Keyword(s):

Phase I ◽

Histone Deacetylase ◽

Graft Versus Host Disease ◽

Histone Deacetylase Inhibitor ◽

Phase I Trial ◽

Primary Therapy ◽

Host Disease ◽

Graft Versus Host ◽

Deacetylase Inhibitor ◽

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A Phase I/II Trial Evaluating the Use of a Histone Deacetylase Inhibitor LBH589 in Addition to Corticosteroids in Patients with Acute Graft Versus Host Disease

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2012.11.515 ◽

2013 ◽

Vol 19 (2) ◽

pp. S337-S338 ◽

Author(s):

Lia Elena Perez ◽

Hugo Fernandez ◽

Marcie Tomblyn ◽

Frederick Locke ◽

Teresa Field ◽

...

Keyword(s):

Phase I ◽

Histone Deacetylase ◽

Graft Versus Host Disease ◽

Histone Deacetylase Inhibitor ◽

Host Disease ◽

Graft Versus Host ◽

Deacetylase Inhibitor ◽

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Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells

International Journal of Cancer ◽

10.1002/ijc.22558 ◽

2007 ◽

Vol 121 (3) ◽

pp. 656-665 ◽

Author(s):

Takashi Kumagai ◽

Naoki Wakimoto ◽

Dong Yin ◽

Sigal Gery ◽

Norihiko Kawamata ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Human Pancreatic Cancer ◽

Suberoylanilide Hydroxamic Acid ◽

Pancreatic Cancer Cells ◽

Deacetylase Inhibitor

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16 Donor pretreatment with progenipoietin-1 prevents acute graft-versus-host disease in an IL-10 dependent fashion and augments the graft-versus-leukemia effect

Biology of Blood and Marrow Transplantation ◽

10.1016/s1083-8791(03)80017-4 ◽

2003 ◽

Vol 9 (2) ◽

pp. 68

Author(s):

K.P. MacDonald ◽

V. Rowe ◽

C. Filipich ◽

J.K. Welply ◽

J.L. Ferrara ◽

...

Keyword(s):

Graft Versus Host Disease ◽

Host Disease ◽

Graft Versus Host ◽

Graft Versus Leukemia ◽

Donor Pretreatment ◽

Acute Graft ◽

Graft Versus Leukemia Effect

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Treatment of canine haemangiosarcoma with suberoylanilide hydroxamic acid, a histone deacetylase inhibitor

Veterinary and Comparative Oncology ◽

10.1111/j.1476-5810.2004.00057.x ◽

2004 ◽

Vol 2 (4) ◽

pp. 243-248 ◽

Author(s):

L. A. Cohen ◽

B. Powers ◽

S. Amin ◽

D. Desai

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Suberoylanilide Hydroxamic Acid ◽

Deacetylase Inhibitor

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The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Confers Acute Neuroprotection After Intracerebral Hemorrhage in Mice

Translational Stroke Research ◽

10.1007/s12975-015-0421-y ◽

2015 ◽

Vol 7 (2) ◽

pp. 141-148 ◽

Author(s):

Sangeetha Sukumari-Ramesh ◽

Cargill H. Alleyne ◽

Krishnan M. Dhandapani

Keyword(s):

Intracerebral Hemorrhage ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Suberoylanilide Hydroxamic Acid ◽

Deacetylase Inhibitor

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Suberoylanilide Hydroxamic Acid, a Histone Deacetylase Inhibitor, Induces the Production of Anti-inflammatory Cyclodepsipeptides from Beauveria felina

Journal of Natural Products ◽

10.1021/np400143j ◽

2013 ◽

Vol 76 (7) ◽

pp. 1260-1266 ◽

Author(s):

Yu-Ming Chung ◽

Mohamed El-Shazly ◽

Da-Wei Chuang ◽

Tsong-Long Hwang ◽

Teigo Asai ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Suberoylanilide Hydroxamic Acid ◽

Deacetylase Inhibitor ◽

Anti Inflammatory

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