Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1204668109 ◽

2012 ◽

Vol 109 (45) ◽

pp. 18471-18476 ◽

Author(s):

X. Geng ◽

C. Huang ◽

Y. Qin ◽

J. E. McCombs ◽

Q. Yuan ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Intracellular Calcium ◽

Virus Replication ◽

X Protein ◽

Protein Targets ◽

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Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1204652109 ◽

2012 ◽

Vol 109 (45) ◽

pp. 18465-18470 ◽

Author(s):

X. Geng ◽

B. L. Harry ◽

Q. Zhou ◽

R. R. Skeen-Gaar ◽

X. Ge ◽

...

Keyword(s):

Hepatitis B Virus ◽

Caenorhabditis Elegans ◽

Hepatitis B ◽

X Protein ◽

Protein Targets ◽

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Increased expression of phosphoenolpyruvate carboxykinase cytoplasmic isoform by hepatitis B virus X protein affects hepatitis B virus replication

Journal of Medical Virology ◽

10.1002/jmv.25300 ◽

2018 ◽

Vol 91 (2) ◽

pp. 258-264 ◽

Author(s):

Xiaoqiong Tang ◽

Libo Yan ◽

Hong Li ◽

Lingyao Du ◽

Ying Shi ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Virus Replication ◽

Phosphoenolpyruvate Carboxykinase ◽

X Protein ◽

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Hepatitis B virus X protein modulates remodelling of minichromosomes related to hepatitis B virus replication in HepG2 cells

International Journal of Molecular Medicine ◽

10.3892/ijmm.2012.1165 ◽

2012 ◽

Vol 31 (1) ◽

pp. 197-204 ◽

Author(s):

LI LUO ◽

SHU CHEN ◽

QIAN GONG ◽

NA LUO ◽

YU LEI ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Virus Replication ◽

Hepg2 Cells ◽

X Protein ◽

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Hepatitis B Virus X Protein Upregulates Intracellular Calcium Signaling by Binding C-terminal of Orail Protein

Current Medical Science ◽

10.1007/s11596-018-1843-z ◽

2018 ◽

Vol 38 (1) ◽

pp. 26-34 ◽

Author(s):

Jing-hong Yao ◽

Zi-jian Liu ◽

Jian-hua Yi ◽

Jun Wang ◽

Ya-nan Liu

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Calcium Signaling ◽

Intracellular Calcium ◽

X Protein ◽

Intracellular Calcium Signaling ◽

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The roles of hepatitis B virus-encoded X protein in virus replication and the pathogenesis of chronic liver disease

Expert Opinion on Therapeutic Targets ◽

10.1517/14728222.2014.867947 ◽

2014 ◽

Vol 18 (3) ◽

pp. 293-306 ◽

Author(s):

Mark A Feitelson ◽

Barbara Bonamassa ◽

Alla Arzumanyan

Keyword(s):

Liver Disease ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Chronic Liver Disease ◽

Virus Replication ◽

Chronic Liver ◽

X Protein ◽

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Hepatitis B Virus X Protein Induces Cell Death by Causing Loss of Mitochondrial Membrane Potential

Journal of Biological Chemistry ◽

10.1074/jbc.m301606200 ◽

2003 ◽

Vol 278 (24) ◽

pp. 22071-22078 ◽

Author(s):

Yumiko Shirakata ◽

Katsuro Koike

Keyword(s):

Membrane Potential ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Mitochondrial Membrane Potential ◽

Mitochondrial Membrane ◽

X Protein ◽

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Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2011.10.013 ◽

2011 ◽

Vol 415 (1) ◽

pp. 68-74 ◽

Author(s):

Yi Mao ◽

Liang Da ◽

Hong Tang ◽

Jiali Yang ◽

Yinrui Lei ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

X Protein ◽

Apoptotic Pathway ◽

Mitochondrial Apoptotic Pathway ◽

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Hepatitis B Virus X Protein Associated with UV-DDB1 Induces Cell Death in the Nucleus and Is Functionally Antagonized by UV-DDB2

Journal of Biological Chemistry ◽

10.1074/jbc.m205722200 ◽

2002 ◽

Vol 277 (41) ◽

pp. 38847-38854 ◽

Author(s):

Séverine Bontron ◽

Nathalie Lin-Marq ◽

Michel Strubin

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

X Protein ◽

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Hepatitis B virus X protein activates proteasomal activator 28 gamma expression via upregulation of p53 levels to stimulate virus replication

Journal of General Virology ◽

10.1099/jgv.0.001054 ◽

2018 ◽

Vol 99 (5) ◽

pp. 655-666 ◽

Author(s):

Sujeong Yeom ◽

Hyerin Jeong ◽

Soo Shin Kim ◽

Kyung Lib Jang

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Virus Replication ◽

X Protein ◽

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Hepatitis B virus X protein disturbs intracellular calcium signaling by binding to Orai1 protein

World Chinese Journal of Digestology ◽

10.11569/wcjd.v22.i1.80 ◽

2014 ◽

Vol 22 (1) ◽

pp. 80

Author(s):

Jun Wang

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Calcium Signaling ◽

Intracellular Calcium ◽

X Protein ◽

Intracellular Calcium Signaling ◽

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