scholarly journals Measurement and purification of human chromosomes by flow cytometry and sorting.

1979 ◽  
Vol 76 (3) ◽  
pp. 1382-1384 ◽  
Author(s):  
A. V. Carrano ◽  
J. W. Gray ◽  
R. G. Langlois ◽  
K. J. Burkhart-Schultz ◽  
M. A. Van Dilla
1979 ◽  
Vol 27 (1) ◽  
pp. 305-310 ◽  
Author(s):  
D H Moore

A new method for decomposing flow cytometry histograms of isolated human metaphase chromosomes is described and tested. The method is based on fitting a template, composed of the means of all chromosomes of a normal karyotype to the flow histogram. The utility of the method is demonstrated by application to flow measurements of chromosomes from a normal person and comparing the results with those obtained by conventional cytophotometry. The power of the method for detecting gross chromosomal abnormalities, such as trisomy 21, as well as more subtle variations such as a single translocation, is determined for simulated data.


1982 ◽  
Vol 79 (24) ◽  
pp. 7876-7880 ◽  
Author(s):  
R. G. Langlois ◽  
L. C. Yu ◽  
J. W. Gray ◽  
A. V. Carrano

1983 ◽  
Vol 119 (2) ◽  
pp. 161-168 ◽  
Author(s):  
Judith A. Fantes ◽  
D.K. Green ◽  
J.K. Elder ◽  
Patricia Malloy ◽  
H.J. Evans

1987 ◽  
Vol 31 (4) ◽  
pp. 195-199
Author(s):  
Mitsugu Fukuda ◽  
Mochihiko Ohashi

1986 ◽  
Vol 41 (1) ◽  
pp. 14-21 ◽  
Author(s):  
P. Harris ◽  
E. Boyd ◽  
B.D. Young ◽  
M.A. Ferguson-Smith

Author(s):  
Jason Stanley ◽  
Henry Hui ◽  
Wendy Erber ◽  
Britt Clynick ◽  
Kathy Fuller

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