scholarly journals Long-term increases in neurotransmitter release from neuronal cells expressing a constitutively active adenylate cyclase from a herpes simplex virus type 1 vector.

1993 ◽  
Vol 90 (16) ◽  
pp. 7603-7607 ◽  
Author(s):  
A. I. Geller ◽  
M. J. During ◽  
J. W. Haycock ◽  
A. Freese ◽  
R. Neve
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Adenylate Cyclase ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neurotransmitter Release ◽  
Neuronal Cells ◽  
Simplex Virus

scholarly journals Herpes simplex virus-mediated human hypoxanthine-guanine phosphoribosyltransferase gene transfer into neuronal cells.

1988 ◽  
Vol 8 (1) ◽  
pp. 457-460 ◽  
Author(s):  
T D Palella ◽  
L J Silverman ◽  
C T Schroll ◽  
F L Homa ◽  
M Levine ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuronal Cells ◽  
Neurological Dysfunction ◽  
Hprt Gene ◽  
Hypoxanthine Guanine Phosphoribosyltransferase ◽  
Simplex Virus

The virtually complete deficiency of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT) results in a devastating neurological disease, Lesch-Nyhan syndrome. Transfer of the HPRT gene into fibroblasts and lymphoblasts in vitro and into hematopoietic cells in vivo has been accomplished by other groups with retroviral-derived vectors. It appears to be necessary, however, to transfer the HPRT gene into neuronal cells to correct the neurological dysfunction of this disorder. The neurotropic virus herpes simplex virus type 1 has features that make it suitable for use as a vector to transfer the HPRT gene into neuronal tissue. This report describes the isolation of an HPRT-deficient rat neuroma cell line, designated B103-4C, and the construction of a recombinant herpes simplex virus type 1 that contained human HPRT cDNA. These recombinant viruses were used to infect B103-4C cells. Infected cells expressed HPRT activity which was human in origin.

scholarly journals Stable induction of a 51K cellular protein in neuronal cells surviving herpes simplex virus type 1 infection

Virology ◽  
1985 ◽  
Vol 142 (2) ◽  
pp. 398-405
Author(s):  
Alan L. Goldin ◽  
Rozanne M. Sandri-Goldin ◽  
Joseph C. Glorioso ◽  
Myron Levine
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuronal Cells ◽  
Cellular Protein ◽  
Simplex Virus

Incidence, Outcome, and Long-Term Consequences of Herpes Simplex Virus Type 1 Reactivation Presenting as a Facial Rash in Intubated Adult Burn Patients Treated with Acyclovir

2002 ◽  
Vol 53 (1) ◽  
pp. 86-89 ◽  
Author(s):  
Philip E. Fidler ◽  
Bonnie T. Mackool ◽  
David A. Schoenfeld ◽  
Maryanne Malloy ◽  
John T. Schulz ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Burn Patients ◽  
Long Term Consequences ◽  
Simplex Virus

Disseminated herpes simplex virus type-1 infection in long-term usage of everolimus

2012 ◽  
Vol 40 (1) ◽  
pp. 84-85 ◽  
Author(s):  
Monji Koga ◽  
Ichiro Nakayama ◽  
Teppei Sakai ◽  
Kaori Koga ◽  
Shinichi Imafuku ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Simplex Virus

Herpes simplex virus type 1 modulates cellular gene expression during quiescent infection of neuronal cells

2008 ◽  
Vol 153 (7) ◽  
pp. 1335-1345 ◽  
Author(s):  
Robert J. Danaher ◽  
Brandon S. McGarrell ◽  
Arnold J. Stromberg ◽  
Craig S. Miller
Keyword(s):  
Gene Expression ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Neuronal Cells ◽  
Cellular Gene ◽  
Cellular Gene Expression ◽  
Simplex Virus

Development of an aciclovir implant for the effective long-term control of herpes simplex virus type-1 infection in Vero cells and in experimentally infected SKH-1 mice

2007 ◽  
Vol 30 (5) ◽  
pp. 428-435 ◽  
Author(s):  
Tory P. Johnson ◽  
Robin Frey ◽  
Melissa Modugno ◽  
Timothy P. Brennan ◽  
Barry J. Margulies
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Vero Cells ◽  
Simplex Virus

Long-Term Expression Driven by Herpes Simplex Virus Type-1 Amplicons May Fail Due to Eventual Degradation or Extrusion of Introduced Transgenes

2000 ◽  
Vol 165 (1) ◽  
pp. 58-65 ◽  
Author(s):  
David J. Tsai ◽  
Jill J. Ho ◽  
Clare R. Ozawa ◽  
Robert M. Sapolsky
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Simplex Virus

scholarly journals Histone deacetylase inhibitors induce reactivation of herpes simplex virus type 1 in a latency-associated transcript–independent manner in neuronal cells

2005 ◽  
Vol 11 (3) ◽  
pp. 306-317 ◽  
Author(s):  
Robert J Danaher ◽  
Robert J Jacob ◽  
Marion R Steiner ◽  
Will R Allen ◽  
James M Hill ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Histone Deacetylase ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Histone Deacetylase Inhibitors ◽  
Neuronal Cells ◽  
Independent Manner ◽  
Simplex Virus

Herpes simplex virus type 1 long-term persistence, latency, and reactivation in infected Burkitt lymphoma cells

1991 ◽  
Vol 117 (3-4) ◽  
pp. 251-267 ◽  
Author(s):  
W. Hampl ◽  
S. Conrad ◽  
A. K. Kleinschmidt
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Burkitt Lymphoma ◽  
Lymphoma Cells ◽  
Simplex Virus
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