Purification and Cloning of Hepatocyte Growth Factor Activator Inhibitor Type 2, a Kunitz-type Serine Protease Inhibitor

Journal of Biological Chemistry ◽

10.1074/jbc.272.44.27558 ◽

1997 ◽

Vol 272 (44) ◽

pp. 27558-27564 ◽

Author(s):

Toshiya Kawaguchi ◽

Li Qin ◽

Takeshi Shimomura ◽

Jun Kondo ◽

Kouji Matsumoto ◽

...

Keyword(s):

Growth Factor ◽

Protease Inhibitor ◽

Serine Protease Inhibitor ◽

Hepatocyte Growth Factor Activator ◽

Kunitz Type ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Defect of Hepatocyte Growth Factor Activator Inhibitor Type 1/Serine Protease Inhibitor, Kunitz Type 1 (Hai-1/Spint1) Leads to Ichthyosis-Like Condition and Abnormal Hair Development in Mice

American Journal Of Pathology ◽

10.2353/ajpath.2008.071142 ◽

2008 ◽

Vol 173 (5) ◽

pp. 1464-1475 ◽

Author(s):

Koki Nagaike ◽

Makiko Kawaguchi ◽

Naoki Takeda ◽

Tsuyoshi Fukushima ◽

Akira Sawaguchi ◽

...

Keyword(s):

Growth Factor ◽

Serine Protease Inhibitor ◽

Hepatocyte Growth Factor Activator ◽

Hair Development ◽

Kunitz Type ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Functional characterization of Kunitz domains in hepatocyte growth factor activator inhibitor type 2

FEBS Letters ◽

10.1016/s0014-5793(98)01105-3 ◽

1998 ◽

Vol 436 (1) ◽

pp. 111-114 ◽

Author(s):

Li Qin ◽

Kimitoshi Denda ◽

Takeshi Shimomura ◽

Toshiya Kawaguchi ◽

Naomi Kitamura

Keyword(s):

Growth Factor ◽

Hepatocyte Growth Factor ◽

Functional Characterization ◽

Hepatocyte Growth Factor Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Reduced expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin (HAI-2/PB) in human glioblastomas: Implication for anti-invasive role of HAI-2/PB in glioblastoma cells

International Journal of Cancer ◽

10.1002/ijc.1349 ◽

2001 ◽

Vol 93 (3) ◽

pp. 339-345 ◽

Author(s):

Ryouichi Hamasuna ◽

Hiroaki Kataoka ◽

Jing-Yan Meng ◽

Hiroshi Itoh ◽

Takuzou Moriyama ◽

...

Keyword(s):

Growth Factor ◽

Hepatocyte Growth Factor ◽

Glioblastoma Cells ◽

Hepatocyte Growth Factor Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Clinical relevance of hepsin and hepatocyte growth factor activator inhibitor type 2 expression in renal cell carcinoma

Cancer Science ◽

10.1111/j.1349-7006.2007.00412.x ◽

2007 ◽

Vol 98 (4) ◽

pp. 491-498 ◽

Author(s):

Hironori Betsunoh ◽

Shoichiro Mukai ◽

Yutaka Akiyama ◽

Tsuyoshi Fukushima ◽

Naoki Minamiguchi ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Growth Factor ◽

Clinical Relevance ◽

Hepatocyte Growth Factor Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Characterization of transcripts generated from mouse hepatocyte growth factor activator inhibitor type 2 (HAI-2) and HAI-2-related small peptide (H2RSP) genes: chimeric mRNA transcribed from both HAI-2 and H2RSP genes is detected in human but not in mouse

Biochemical and Biophysical Research Communications ◽

10.1016/s0006-291x(03)00154-2 ◽

2003 ◽

Vol 302 (2) ◽

pp. 345-353 ◽

Author(s):

Seiji Naganuma ◽

Hiroshi Itoh ◽

Shuichiro Uchiyama ◽

Hiroyuki Tanaka ◽

Koki Nagaike ◽

...

Keyword(s):

Growth Factor ◽

Small Peptide ◽

Mouse Hepatocyte ◽

Hepatocyte Growth Factor Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Mouse hepatocyte growth factor activator inhibitor type 1 (HAI-1) and type 2 (HAI-2)/placental bikunin genes and their promoters

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ◽

10.1016/s0167-4781(01)00216-0 ◽

2001 ◽

Vol 1519 (1-2) ◽

pp. 92-95 ◽

Author(s):

Hiroshi Itoh ◽

Hiroaki Kataoka ◽

Jing Yan Meng ◽

Ryouichi Hamasuna ◽

Naomi Kitamura ◽

...

Keyword(s):

Growth Factor ◽

Hepatocyte Growth Factor ◽

Mouse Hepatocyte ◽

Hepatocyte Growth Factor Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Hepatocyte Growth Factor Activator Inhibitor, a Novel Kunitz-type Serine Protease Inhibitor

Journal of Biological Chemistry ◽

10.1074/jbc.272.10.6370 ◽

1997 ◽

Vol 272 (10) ◽

pp. 6370-6376 ◽

Author(s):

Takeshi Shimomura ◽

Kimitoshi Denda ◽

Akiko Kitamura ◽

Toshiya Kawaguchi ◽

Masahiro Kito ◽

...

Keyword(s):

Growth Factor ◽

Hepatocyte Growth Factor ◽

Protease Inhibitor ◽

Serine Protease ◽

Serine Protease Inhibitor ◽

Hepatocyte Growth Factor Activator ◽

Kunitz Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Serum hepatocyte growth factor activator inhibitor type I (HAI-I) and type 2 (HAI-2) in prostate cancer

The Prostate ◽

10.1002/pros.20301 ◽

2006 ◽

Vol 66 (5) ◽

pp. 447-452 ◽

Author(s):

Osamu Nagakawa ◽

Toshiya Yamagishi ◽

Takuya Akashi ◽

Kazuhiro Nagaike ◽

Hideki Fuse

Keyword(s):

Prostate Cancer ◽

Growth Factor ◽

Hepatocyte Growth Factor ◽

Type I ◽

Hepatocyte Growth Factor Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Potent Inhibition and Global Co-localization Implicate the Transmembrane Kunitz-type Serine Protease Inhibitor Hepatocyte Growth Factor Activator Inhibitor-2 in the Regulation of Epithelial Matriptase Activity

Journal of Biological Chemistry ◽

10.1074/jbc.m801970200 ◽

2008 ◽

Vol 283 (43) ◽

pp. 29495-29504 ◽

Author(s):

Roman Szabo ◽

John P. Hobson ◽

Karin List ◽

Alfredo Molinolo ◽

Chen-Yong Lin ◽

...

Keyword(s):

Growth Factor ◽

Hepatocyte Growth Factor ◽

Protease Inhibitor ◽

Serine Protease ◽

Serine Protease Inhibitor ◽

Potent Inhibition ◽

Hepatocyte Growth Factor Activator ◽

Kunitz Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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Hepatocyte growth factor activator inhibitor type-2 (HAI-2)/SPINT2 contributes to invasive growth of oral squamous cell carcinoma cells

10.18632/oncotarget.24450 ◽

2018 ◽

Vol 9 (14) ◽

pp. 11691-11706 ◽

Author(s):

Koji Yamamoto ◽

Makiko Kawaguchi ◽

Takeshi Shimomura ◽

Aya Izumi ◽

Kazuomi Konari ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Growth Factor ◽

Carcinoma Cells ◽

Invasive Growth ◽

Hepatocyte Growth Factor Activator ◽

Inhibitor Type ◽

Activator Inhibitor Type ◽

Hepatocyte Growth ◽

Activator Inhibitor

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