scholarly journals The Crystal Structure of Cytochrome P450 4B1 (CYP4B1) Monooxygenase Complexed with Octane Discloses Several Structural Adaptations for ω-Hydroxylation

2017 ◽  
Vol 292 (13) ◽  
pp. 5610-5621 ◽  
Author(s):  
Mei-Hui Hsu ◽  
Brian R. Baer ◽  
Allan E. Rettie ◽  
Eric F. Johnson
Keyword(s):  
Crystal Structure ◽  
Cytochrome P450 ◽  
Cytochrome P450 4B1 ◽  
Structural Adaptations

scholarly journals Differential cytotoxicity and bystander effect of the rabbit cytochrome P450 4B1 enzyme gene by two different prodrugs: Implications for pharmacogene therapy

2002 ◽  
Vol 9 (2) ◽  
pp. 178-188 ◽  
Author(s):  
Susanne Frank ◽  
Sabine Steffens ◽  
Ute Fischer ◽  
Aurelia Tlolko ◽  
Nikolai G Rainov ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Bystander Effect ◽  
Enzyme Gene ◽  
Cytochrome P450 4B1

scholarly journals Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1

2018 ◽  
Vol 293 (29) ◽  
pp. 11433-11446 ◽  
Author(s):  
Gareth K. Jennings ◽  
Mei-Hui Hsu ◽  
Lisa S. Shock ◽  
Eric F. Johnson ◽  
John C Hackett
Keyword(s):  
Cytochrome P450 ◽  
Noncovalent Interactions ◽  
Cytochrome P450 4B1 ◽  
Heme Distortion

scholarly journals Crystal Structure of Human Cytochrome P450 2D6

2005 ◽  
Vol 281 (11) ◽  
pp. 7614-7622 ◽  
Author(s):  
Paul Rowland ◽  
Frank E. Blaney ◽  
Martin G. Smyth ◽  
Jo J. Jones ◽  
Vaughan R. Leydon ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Cytochrome P450 ◽  
Cytochrome P450 2D6 ◽  
Human Cytochrome ◽  
P450 2D6

scholarly journals A Rational Approach to Re-engineer Cytochrome P450 2B1 Regioselectivity Based on the Crystal Structure of Cytochrome P450 2C5

2003 ◽  
Vol 278 (19) ◽  
pp. 17178-17184 ◽  
Author(s):  
Santosh Kumar ◽  
Emily E. Scott ◽  
Hong Liu ◽  
James R. Halpert
Keyword(s):  
Crystal Structure ◽  
Cytochrome P450 ◽  
Rational Approach

scholarly journals Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis

2002 ◽  
Vol 277 (49) ◽  
pp. 47476-47485 ◽  
Author(s):  
Katja Zerbe ◽  
Olena Pylypenko ◽  
Francesca Vitali ◽  
Weiwen Zhang ◽  
Severine Rouset ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Cytochrome P450 ◽  
Coupling Reaction

scholarly journals Crystal Structure of a Thermophilic Cytochrome P450 from the ArchaeonSulfolobus solfataricus

2000 ◽  
Vol 275 (40) ◽  
pp. 31086-31092 ◽  
Author(s):  
Jason K. Yano ◽  
Laura S. Koo ◽  
David J. Schuller ◽  
Huiying Li ◽  
Paul R. Ortiz de Montellano ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Cytochrome P450

New Prodrug Activation Gene Therapy for Cancer Using Cytochrome P450 4B1 and 2-Aminoanthracene/4-Ipomeanol

1998 ◽  
Vol 9 (9) ◽  
pp. 1261-1273 ◽  
Author(s):  
Nikolai G. Rainov ◽  
Karl-Ulrich Dobberstein ◽  
Miguel Sena-Esteves ◽  
Ulrich Herrlinger ◽  
Christof M. Kramm ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Cytochrome P450 ◽  
Prodrug Activation ◽  
Cytochrome P450 4B1

scholarly journals Inhibition of VEGF expression and corneal neovascularization by siRNA targeting cytochrome P450 4B1

2007 ◽  
Vol 84 (3-4) ◽  
pp. 116-127 ◽  
Author(s):  
Francesca Seta ◽  
Kiran Patil ◽  
Lars Bellner ◽  
Alexandre Mezentsev ◽  
Rowena Kemp ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Corneal Neovascularization ◽  
Vegf Expression ◽  
Cytochrome P450 4B1
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