scholarly journals Regulated Exocytosis Contributes to Protein Kinase C Potentiation of Vanilloid Receptor Activity

2004 ◽  
Vol 279 (24) ◽  
pp. 25665-25672 ◽  
Author(s):  
Cruz Morenilla-Palao ◽  
Rosa Planells-Cases ◽  
Nuria García-Sanz ◽  
Antonio Ferrer-Montiel
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Vanilloid Receptor ◽  
Receptor Activity ◽  
Regulated Exocytosis ◽  
Kinase C

Regulation of exocytosis by protein kinase C

2005 ◽  
Vol 33 (6) ◽  
pp. 1341-1344 ◽  
Author(s):  
A. Morgan ◽  
R.D. Burgoyne ◽  
J.W. Barclay ◽  
T.J. Craig ◽  
G.R. Prescott ◽  
...  
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Cell Types ◽  
Neuroendocrine Cells ◽  
Protein Targets ◽  
Site Specific ◽  
Regulated Exocytosis ◽  
Kinase C ◽  
Pkc Protein Kinase C

PKC (protein kinase C) has been known for many years to modulate regulated exocytosis in a wide variety of cell types. In neurons and neuroendocrine cells, PKC regulates several different stages of the exocytotic process, suggesting that these multiple actions of PKC are mediated by phosphorylation of distinct protein targets. In recent years, a variety of exocytotic proteins have been identified as PKC substrates, the best characterized of which are SNAP-25 (25 kDa synaptosome-associated protein) and Munc18. In the present study, we review recent evidence suggesting that site-specific phosphorylation of SNAP-25 and Munc18 by PKC regulates distinct stages of exocytosis.

Induction of vanilloid receptor channel activity by protein kinase C

Nature ◽  
2000 ◽  
Vol 408 (6815) ◽  
pp. 985-990 ◽  
Author(s):  
Louis S. Premkumar ◽  
Gerard P. Ahern
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Vanilloid Receptor ◽  
Channel Activity ◽  
Kinase C ◽  
Receptor Channel

scholarly journals Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamide

2001 ◽  
Vol 534 (3) ◽  
pp. 813-825 ◽  
Author(s):  
Vittorio Vellani ◽  
Sarah Mapplebeck ◽  
Andrea Moriondo ◽  
John B. Davis ◽  
Peter A. McNaughton
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Vanilloid Receptor ◽  
Kinase C ◽  
Protein Kinase C Activation

scholarly journals PresynapticN-Methyl-d-aspartate (NMDA) Receptor Activity Is Increased Through Protein Kinase C in Paclitaxel-induced Neuropathic Pain

2016 ◽  
Vol 291 (37) ◽  
pp. 19364-19373 ◽  
Author(s):  
Jing-Dun Xie ◽  
Shao-Rui Chen ◽  
Hong Chen ◽  
Wei-An Zeng ◽  
Hui-Lin Pan
Keyword(s):  
Neuropathic Pain ◽  
Protein Kinase C ◽  
Nmda Receptor ◽  
Protein Kinase ◽  
Receptor Activity ◽  
Kinase C
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