Odontogenic Lemierre’s syndrome with septic superior ophthalmic vein and cavernous sinus thrombophlebitis complicated by blindness and ophthalmoplegia

Orbit ◽  
2021 ◽  
pp. 1-7
Author(s):  
Donald Tran ◽  
Shivesh Varma ◽  
Thomas G. Hardy
2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Samantha Novotny ◽  
Kenneth Serrano ◽  
Danielle Bazer ◽  
Louis Manganas

Background. Lemierre’s syndrome is a rare condition of internal jugular vein thrombosis following oropharyngeal infection. While it usually results from Fusobacterium necrophorum infection, atypical cases associated with other pathogens have been reported. Objective. To describe a unique case of pediatric Lemierre’s syndrome with Streptococcus viridans infection resulting in cavernous sinus thrombosis and oculomotor, trochlear, and abducens nerve palsies. Case Report. A 14-year-old female initially presented after six days of fever, myalgias, and sore throat and was admitted for hyperbilirubinemia and acute kidney injury. She developed a fixed, dilated pupil with complete ophthalmoplegia, ptosis, and severe pain. Imaging revealed retromandibular space abscess, external and internal jugular vein thrombosis, cavernous sinus thrombosis, internal carotid artery stenosis, pulmonary embolism, and bilateral pneumonia. She was diagnosed with Lemierre’s syndrome with cultures positive for Streptococcus viridans and treated with a combination of antibiotics and anticoagulation. Conclusion and Relevance. Both antibiotics and anticoagulation were effective management for this Lemierre’s syndrome patient with cavernous sinus thrombosis. Early diagnosis and treatment of Lemierre’s syndrome is essential. A multidisciplinary treatment team is beneficial for managing the sequelae of this condition.


2021 ◽  
Vol 14 (3) ◽  
pp. e238521
Author(s):  
Peerawat Sukkul ◽  
Narongrit Kasemsap

Lemierre’s syndrome is a rare multisystemic infection beginning in oropharynx commonly caused by oral anaerobic organisms and leading to internal jugular vein thrombosis with septic emboli. Here, we describe a 45-year-old woman with hypertension and unrecognised type 2 diabetes who presented to a community hospital with fever, double vision and septic shock. Examination showed neck pain aggravated by neck flexion, limited ocular movement of right lateral rectus, left medial rectus and left superior oblique and incomplete ptosis of the left eye. These symptoms were suggestive of bilateral cavernous sinus syndrome. CT of the brain showed bilateral proximal internal jugular vein and cavernous sinus thrombosis. CT angiography revealed septic emboli at both upper lungs. The patient had good improvement of neurological symptoms after dental extraction, intravenous antibiotic and anticoagulant.


Author(s):  
Adrian Budhram ◽  
Basavaraj Shettar ◽  
Donald H. Lee ◽  
Michael Silverman ◽  
Kaveri Gupta

2017 ◽  
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pp. 887-888 ◽  
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Hirotoshi Matsui

2020 ◽  
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Giovanni D'erme ◽  
Massimo Galli ◽  
Francesca R. Federici ◽  
Andrea Colizza ◽  
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pp. bcr-2017-220110 ◽  
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IDCases ◽  
2021 ◽  
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Author(s):  
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Alberto Paniz-Mondolfi ◽  
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2008 ◽  
Vol 57 (1) ◽  
pp. 118-120 ◽  
Author(s):  
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Nishanth Murukesh ◽  
M. P. S. Varma ◽  
Ikram M. Sharif ◽  
Gerard Glynn

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