Matrix Metalloproteinase-13 (MMP-13, Collagenase-3) is Highly Expressed in Human Tooth Pulp

Connective Tissue Research ◽

10.1080/03008200490885788 ◽

2004 ◽

Vol 45 (4-5) ◽

pp. 231-237 ◽

Author(s):

Merja Sulkala ◽

Virve Pääkkönen ◽

Markku Larmas ◽

Tuula Salo ◽

Leo Tjäderhane

Keyword(s):

Matrix Metalloproteinase ◽

Human Tooth ◽

Matrix Metalloproteinase 13

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Faculty Opinions recommendation of Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1144893.601985 ◽

2009 ◽

Author(s):

Ivan Martin

Keyword(s):

Matrix Metalloproteinase ◽

Intramembranous Ossification ◽

Matrix Metalloproteinase 13 ◽

Skeletal Regeneration

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Faculty Opinions recommendation of Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1326012.796128 ◽

2009 ◽

Author(s):

Yefu Li ◽

Lin Xu

Keyword(s):

Matrix Metalloproteinase ◽

Osteoarthritic Cartilage ◽

Chondrocyte Hypertrophy ◽

Matrix Metalloproteinase 13 ◽

Cartilage Erosion ◽

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Faculty Opinions recommendation of MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3636965.3355054 ◽

2010 ◽

Author(s):

Francisco Blanco ◽

Ignacio Rego-Perez

Keyword(s):

Matrix Metalloproteinase ◽

Matrix Metalloproteinase 13 ◽

Osteoarthritis Chondrocytes

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Faculty Opinions recommendation of Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717960792.793463776 ◽

2012 ◽

Author(s):

Francisco Blanco ◽

Cristina Ruiz-Romero

Keyword(s):

Articular Cartilage ◽

Matrix Metalloproteinase ◽

Matrix Metalloproteinase 13

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Faculty Opinions recommendation of Bone marrow-derived myofibroblasts are the providers of pro-invasive matrix metalloproteinase 13 in primary tumor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717961060.793463864 ◽

2012 ◽

Author(s):

Giulio Gabbiani

Keyword(s):

Bone Marrow ◽

Matrix Metalloproteinase ◽

Primary Tumor ◽

Matrix Metalloproteinase 13

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Faculty Opinions recommendation of MicroRNA-320 regulates matrix metalloproteinase-13 expression in chondrogenesis and interleukin-1β-induced chondrocyte responses.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726079912.793556152 ◽

2019 ◽

Author(s):

David Young

Keyword(s):

Matrix Metalloproteinase ◽

Interleukin 1Β ◽

Matrix Metalloproteinase 13

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Peptidergic nerves in human tooth pulp

European Journal Of Oral Sciences ◽

10.1111/j.1600-0722.1984.tb00898.x ◽

1984 ◽

Vol 92 (4) ◽

pp. 319-324

Author(s):

MATS GRÖNBLAD ◽

PÄIVI LIESI ◽

ANNE MARIE MUNCK

Keyword(s):

Human Tooth ◽

Peptidergic Nerves

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Increased Matrix Metalloproteinase-13 Production With Aging by Human Articular Chondrocytes in Response to Catabolic Stimuli

The Journals of Gerontology Series A ◽

10.1093/gerona/60.9.1118 ◽

2005 ◽

Vol 60 (9) ◽

pp. 1118-1124 ◽

Author(s):

C. B. Forsyth ◽

A. Cole ◽

G. Murphy ◽

J. L. Bienias ◽

H.-J. Im ◽

...

Keyword(s):

Matrix Metalloproteinase ◽

Articular Chondrocytes ◽

Human Articular Chondrocytes ◽

Matrix Metalloproteinase 13

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Brief Report: Stress-Inducible Nuclear Protein 1 Regulates Matrix Metalloproteinase 13 Expression in Human Articular Chondrocytes

Arthritis & Rheumatology ◽

10.1002/art.38391 ◽

2014 ◽

Vol 66 (5) ◽

pp. 1266-1271 ◽

Author(s):

Raghunatha R. Yammani ◽

Richard F. Loeser

Keyword(s):

Matrix Metalloproteinase ◽

Nuclear Protein ◽

Articular Chondrocytes ◽

Human Articular Chondrocytes ◽

Matrix Metalloproteinase 13

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Osteopontin Promotes Expression of Matrix Metalloproteinase 13 through NF-κB Signaling in Osteoarthritis

BioMed Research International ◽

10.1155/2016/6345656 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Author(s):

Yusheng Li ◽

Wei Jiang ◽

Hua Wang ◽

Zhenhan Deng ◽

Chao Zeng ◽

...

Keyword(s):

Matrix Metalloproteinase ◽

Matrix Metalloproteinase 13

Osteopontin (OPN) is associated with the severity and progression of osteoarthritis (OA); however, the mechanism of OPN in the pathogenesis of OA is unknown. In this study, we found that OA patients had higher abundance of OPN and matrix metalloproteinase 13 (MMP13). In chondrocytes, we showed that OPN promoted the production of MMP13 and activation of NF-κB pathway by increasing the abundance of p65 and phosphorylated p65 and translocation of p65 protein from cytoplasm to nucleus. Notably, inhibition of NF-κB pathway by inhibitor suppressed the production of MMP13 induced by OPN treatment. In conclusion, OPN induces production of MMP13 through activation of NF-κB pathway.

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