Pre-plasticization of thermal binder facilitates processing and granule growth during melt granulation of gabapentin using co-rotating twin screw extruder

2020 ◽  
Vol 46 (12) ◽  
pp. 1971-1978
Author(s):  
Jamie E. Spahn ◽  
Feng Zhang
Keyword(s):  
Twin Screw Extruder ◽  
Screw Extruder ◽  
Twin Screw ◽  
Melt Granulation ◽  
Granule Growth

Hot-Melt Granulation in a Twin Screw Extruder: Effects of Processing on Formulations with Caffeine and Ibuprofen

2013 ◽  
Vol 102 (12) ◽  
pp. 4330-4336 ◽  
Author(s):  
Sharleen Weatherley ◽  
B.O. MU ◽  
Michael R. Thompson ◽  
Paul J. Sheskey ◽  
Kevin P. O'Donnell
Keyword(s):  
Twin Screw Extruder ◽  
Screw Extruder ◽  
Twin Screw ◽  
Hot Melt Granulation ◽  
Hot Melt ◽  
Melt Granulation

Application of Melt Granulation Technology Using Twin-screw Extruder in Development of High-dose Modified-Release Tablet Formulation

2011 ◽  
Vol 100 (5) ◽  
pp. 1923-1934 ◽  
Author(s):  
Madhav Vasanthavada ◽  
Yanfeng Wang ◽  
Thomas Haefele ◽  
Jay P. Lakshman ◽  
Manisha Mone ◽  
...  
Keyword(s):  
Tablet Formulation ◽  
High Dose ◽  
Twin Screw Extruder ◽  
Modified Release ◽  
Screw Extruder ◽  
Twin Screw ◽  
Granulation Technology ◽  
Melt Granulation ◽  
Release Tablet

Melt granulation using a twin-screw extruder: A case study

2006 ◽  
Vol 326 (1-2) ◽  
pp. 89-93 ◽  
Author(s):  
Barbara Van Melkebeke ◽  
Brenda Vermeulen ◽  
Chris Vervaet ◽  
Jean Paul Remon
Keyword(s):  
Twin Screw Extruder ◽  
Screw Extruder ◽  
Twin Screw ◽  
Melt Granulation

Effect of binders on the release rates of direct molded verapamil tablets using twin-screw extruder in melt granulation

2014 ◽  
Vol 463 (1) ◽  
pp. 89-97 ◽  
Author(s):  
David Cheng Thiam Tan ◽  
William Wei Lim Chin ◽  
En Hui Tan ◽  
Shiqi Hong ◽  
Wei Gu ◽  
...  
Keyword(s):  
Twin Screw Extruder ◽  
Screw Extruder ◽  
Release Rates ◽  
Twin Screw ◽  
Melt Granulation

Reactive Blending in a Twin Screw Extruder

1996 ◽  
Vol 11 (2) ◽  
pp. 139-146 ◽  
Author(s):  
A. De Loor ◽  
P. Cassagnau ◽  
A. Michel ◽  
L. Delamare ◽  
B. Vergnes
Keyword(s):  
Twin Screw Extruder ◽  
Reactive Blending ◽  
Screw Extruder ◽  
Twin Screw
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