Enzymic Hydrolysis of Methyl 2,3-O-Acetyl-5-Deoxy-α and β-D-Xylofuranosides - An Active-Site Model of Pig Liver Esterase

1997 ◽  
Vol 16 (7) ◽  
pp. 1011-1028 ◽  
Author(s):  
Jitka Moravcová ◽  
Zita Vanclová ◽  
Jindra Čapková ◽  
Karel Kefurt ◽  
Jan Staněk

ChemInform ◽  
2010 ◽  
Vol 29 (4) ◽  
pp. no-no
Author(s):  
J. MORAVCOVA ◽  
Z. VANCLOVA ◽  
J. CAPKOVA ◽  
K. KEFURT ◽  
J. STANEK


1994 ◽  
Vol 59 (10) ◽  
pp. 2729-2732 ◽  
Author(s):  
Louis Provencher ◽  
J. Bryan Jones




2000 ◽  
Vol 65 (10) ◽  
pp. 1619-1629 ◽  
Author(s):  
Jitka Moravcová ◽  
Karel Kefurt ◽  
Romana Hladůvková ◽  
Jan Staněk

Methyl 2,3,4-tri-O-acetyl-β-D-arabinopyranoside (1), methyl 2,3,4-tri-O-acetyl-β-D-ribopyranoside (2), and methyl 2,3,5-tri-O-acetyl-β-D-ribofuranoside (3) were deacetylated in porcine liver esterase-catalyzed reactions. Triacetate 1 gave methyl 3,4-di-O-acetyl-β-D-arabinopyranoside in 70% preparative yield while the regioselectivities found for the substrates 2 and 3 were substantially lower. Both the Michaelis constant and maximum rate were calculated for deacetylation of 1, 2, and 3. The results were interpreted using an active site model for the esterase proposed by Jones.







1988 ◽  
Vol 29 (32) ◽  
pp. 3951-3954 ◽  
Author(s):  
Masahisa Nakada ◽  
Susumu Kobayashi ◽  
Masaji Ohno ◽  
Shigeo Iwasaki ◽  
Shigenobu Okuda


Sign in / Sign up

Export Citation Format

Share Document