Problem drinking in relation to treatment outcome among opiate addicts in methadone maintenance treatment

2007 ◽  
Vol 26 (1) ◽  
pp. 55-63 ◽  
Author(s):  
M. STENBACKA ◽  
O. BECK ◽  
A. LEIFMAN ◽  
A. ROMELSJÖ ◽  
A. HELANDER
Keyword(s):  
Treatment Outcome ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Problem Drinking ◽  
Opiate Addicts

Sleep quality in heroin addicts under methadone maintenance treatment

2012 ◽  
Vol 24 (6) ◽  
pp. 356-360 ◽  
Author(s):  
Wen-Yu Hsu ◽  
Nan-Ying Chiu ◽  
Jui-Ting Liu ◽  
Chieh-Hui Wang ◽  
Ting-Gang Chang ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Sleep Disturbance ◽  
Sleep Disorders ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Opiate Withdrawal ◽  
Heroin Addicts ◽  
Methadone Dosage ◽  
Opiate Addicts

Hsu W-Y, Chiu N-Y, Liu J-T, Wang C-H, Chang T-G, Liao Y-C, Kuo P-I. Sleep quality in heroin addicts under methadone maintenance treatment.Background: Sleep disturbance is a common phenomenon among opiate addicts. The side effects of opiate addiction or opiate withdrawal might result in sleep disturbance. However, their problems might be related to sedative medication abuse, alcohol abuse or heroin relapse. Sleep is an important issue in this population.Objective: To evaluate the prevalence of sleep disorders in heroin addicts receiving methadone maintenance treatment (MMT) and analyse the correlation between related factors, such as age at opiate exposure, opiate exposure duration, duration in MMT, methadone current dosage, methadone attendance rate and the severity of sleep disorders.Method: We enrolled 121 heroin addicts who were receiving MMT. We collected data on the duration of insomnia, hypnotic history, Visual Analogue Scale-10 of sleep quality, Pittsburgh Sleep Quality Index (PSQI), methadone dosage, methadone history and opiate history.Results: The mean of the PSQI was 9.1 ± 5.4, and 70.2% of patients had PSQI scores >5, indicating they were poor sleepers. We also found the PSQI scores were correlated significantly with the methadone dosage.Conclusions: The sleep disturbance prevalence rate of opiate addicts under MMT was high in Taiwan, as shown in the previous studies, and the severity of sleep disturbance has been underestimated.

Group Psychotherapy for Opiate Addicts in Methadone Maintenance Treatment – A Controlled Trial

2005 ◽  
Vol 11 (4) ◽  
pp. 163-171 ◽  
Author(s):  
N. Scherbaum ◽  
J. Kluwig ◽  
M. Specka ◽  
D. Krause ◽  
B. Merget ◽  
...  
Keyword(s):  
Group Psychotherapy ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Controlled Trial ◽  
Opiate Addicts

Treatment of Benzodiazepine Dependence in Methadone Maintenance Treatment Patients: A Comparison of Two Therapeutic Modalities and the Role of Psychiatric Comorbidity

2003 ◽  
Vol 37 (4) ◽  
pp. 458-463 ◽  
Author(s):  
Tal Weizman ◽  
Marc Gelkopf ◽  
Yuval Melamed ◽  
Miriam Adelson ◽  
Avraham Bleich
Keyword(s):  
Treatment Outcome ◽  
Treatment Modality ◽  
Methadone Maintenance Treatment ◽  
Maintenance Dose ◽  
Maintenance Treatment ◽  
Psychiatric Comorbidity ◽  
Methadone Maintenance ◽  
Treatment Success ◽  
History Of ◽  
Axis I

Objective: Therapeutic approaches for benzodiazepine (BZD) dependence in patients in methadone maintenance treatment (MMT) have met with limited success. Clonazepam detoxification (CDTX) and clonazepam maintenance treatment (CMT) were compared in an open, clinical naturalistic study on such patients. Methods: Benzodiazepine dependent patients substituted their BZD of abuse for clonazepam and were then either detoxified (CDTX) or a maintenance dose was reached and maintained (CMT). Patients were considered as failing the trial if they either abused BZDs (CDTX group) or abused BZDs over the maintenance dose (CMT group). Treatment outcome was evaluated based upon self and staff reports over 1 year after beginning treatment. Axis I and II psychiatric diagnosis was assessed and methadone dosage and history of abuse was recorded. Results: In the CDTX group, 9/33 (27.3%), were BZD-free after 2 months. In the CMT group, 26/33 (78.8%) refrained from abusing additional BZDs over the maintenance dose after 2 months. The same success rate remained over the entire year. Survival analysis showed CMT to be more successful than the CDTX. Axis I psychiatric comorbidity was found to be positively related to treatment success in the CMT group while axis II antisocial personality disorder was found to be negatively related to treatment success in that group. It had no impact in the CDTX group. Conclusions: Maintenance strategy with clonazepam is a useful BZD treatment modality for BZD-dependent MMT patients with a long-term history of abuse and previous attempts at detoxification. Psychiatric comorbidity may have an important role in choosing the adequate treatment modality and influencing treatment outcome.

Mydriatic Response to Topical Naloxone in Opiate Abusers

1986 ◽  
Vol 148 (1) ◽  
pp. 44-46 ◽  
Author(s):  
A. H. Ghodse ◽  
T. H. Bewley ◽  
M. K. Kearney ◽  
S. E. Smith
Keyword(s):  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Physical Dependence ◽  
Methadone Treatment ◽  
Acute Withdrawal ◽  
Naloxone Hydrochloride ◽  
Opiate Addicts ◽  
Peripheral Action ◽  
Withdrawal Effects

Naloxone hydrochloride eyedrops 1 mg/ml dilated the pupils of 36 out of 47 opiate addicts on methadone maintenance treatment, without precipitation of acute withdrawal effects, but not those of healthy unmedicated subjects. The response in addicts was attenuated by certain ancillary treatments and by withdrawal of methadone treatment. The size of the response suggests some potential clinical use for topical naloxone as a diagnostic test of current opioid influence and possibility of physical dependence. The local mydriatic response, which was restricted to the treated eye, indicates that the effect of opiates on the pupil in man is determined, at least in part, by a peripheral action.

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